Pathological characteristics of thyroid glands from Japanese Black Cattle living in the restricted area of the Fukushima Daiichi Nuclear Power Plant accident
To study the effect of ionizing radiation on thyroid glands, 66 Japanese Black cattle residing in the restricted area of the Fukushima Daiichi Nuclear Power Plant in 2013–2017 were pathologically examined. There were no clinical symptoms of thyroid disease in these cattle. Three cases of goiter and...
Gespeichert in:
| Veröffentlicht in: | Animal science journal 2019-09, Vol.90 (9), p.1333-1339 |
|---|---|
| Hauptverfasser: | , , , , , , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1339 |
|---|---|
| container_issue | 9 |
| container_start_page | 1333 |
| container_title | Animal science journal |
| container_volume | 90 |
| creator | Sasaki, Jun Uehara, Megumi Sato, Itaru Satoh, Hiroshi Deguchi, Yoshitaka Chida, Hiroyuki Natsuhori, Masahiro Murata, Takahisa Ochiai, Kenji Otani, Kumiko Okada, Keiji Ito, Nobuhiko |
| description | To study the effect of ionizing radiation on thyroid glands, 66 Japanese Black cattle residing in the restricted area of the Fukushima Daiichi Nuclear Power Plant in 2013–2017 were pathologically examined. There were no clinical symptoms of thyroid disease in these cattle. Three cases of goiter and seven of atrophy were found in two among the four farms examined. Cases of goiter exhibited normal morphological structure without mass or nodule formation in thyroid glands. Cellular atypia or capsular invasion of the follicular epithelium was absent. The estimated integrated dose of external radiation in goiter cases ranged from maximum 797 mSv to minimum 24 mSv. All lobules in the seven atrophic thyroid glands were affected, but pathological findings, such as inflammatory cell infiltration or stromal fibrosis, were not observed. The estimated integrated dose of external radiation in atrophic thyroids ranged from maximum 589 mSv to minimum 8 mSv. Immunohistochemical analysis of anti‐nitroguanosine and the TUNEL method in goiter and atrophic thyroid glands did not reveal any positive findings. The present study indicates that there was no significant relationship between a radiation effect and pathological findings in any thyroid glands. |
| doi_str_mv | 10.1111/asj.13269 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2283241277</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2283241277</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4439-2f7b1cf8d86affb5478900a4b6e6427c07b68e07b650d74dbba0957f6345fcf93</originalsourceid><addsrcrecordid>eNp1kcFS3SAUhhmnHbW2C1_AYaYrF1EIJISlXqut41hn2q4zJwRuuHLDFYjOfRjftdhYd7I4sPj4zoEfoUNKTmhepxBXJ5SVtdxB-1RwUhBZyg_5zDgvmOR0D32KcUUIFZJUu2iPUUZkXYt99HwHafDOL60Ch9UAAVTSwcZkVcTe4DRsg7c9XjoY-4hN8Gt8DRsYddT43IG6xwtIyWns7KMdl9iO-Y7GQccUbHb1GIKGWaXx5XQ_xcGuAV-AtWqw-HZSTkPAd_5J55rbJAxK2V6P6TP6aMBF_eV1P0B_Lr_9Xnwvbn5e_Vic3RSKcyaL0oiOKtP0TQ3GdBUXjSQEeFfrmpdCEdHVjX6pFekF77sOiKyEqRmvjDKSHaCvs3cT_MOUJ29XfgpjbtmWZcNKTkshMnU8Uyr4GIM27Sbkl4RtS0n7EkSbg2j_BZHZo1fj1K11_0b-__kMnM7Ak3V6-76pPft1PSv_AhJVlH0</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2283241277</pqid></control><display><type>article</type><title>Pathological characteristics of thyroid glands from Japanese Black Cattle living in the restricted area of the Fukushima Daiichi Nuclear Power Plant accident</title><source>Access via Wiley Online Library</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><creator>Sasaki, Jun ; Uehara, Megumi ; Sato, Itaru ; Satoh, Hiroshi ; Deguchi, Yoshitaka ; Chida, Hiroyuki ; Natsuhori, Masahiro ; Murata, Takahisa ; Ochiai, Kenji ; Otani, Kumiko ; Okada, Keiji ; Ito, Nobuhiko</creator><creatorcontrib>Sasaki, Jun ; Uehara, Megumi ; Sato, Itaru ; Satoh, Hiroshi ; Deguchi, Yoshitaka ; Chida, Hiroyuki ; Natsuhori, Masahiro ; Murata, Takahisa ; Ochiai, Kenji ; Otani, Kumiko ; Okada, Keiji ; Ito, Nobuhiko</creatorcontrib><description>To study the effect of ionizing radiation on thyroid glands, 66 Japanese Black cattle residing in the restricted area of the Fukushima Daiichi Nuclear Power Plant in 2013–2017 were pathologically examined. There were no clinical symptoms of thyroid disease in these cattle. Three cases of goiter and seven of atrophy were found in two among the four farms examined. Cases of goiter exhibited normal morphological structure without mass or nodule formation in thyroid glands. Cellular atypia or capsular invasion of the follicular epithelium was absent. The estimated integrated dose of external radiation in goiter cases ranged from maximum 797 mSv to minimum 24 mSv. All lobules in the seven atrophic thyroid glands were affected, but pathological findings, such as inflammatory cell infiltration or stromal fibrosis, were not observed. The estimated integrated dose of external radiation in atrophic thyroids ranged from maximum 589 mSv to minimum 8 mSv. Immunohistochemical analysis of anti‐nitroguanosine and the TUNEL method in goiter and atrophic thyroid glands did not reveal any positive findings. The present study indicates that there was no significant relationship between a radiation effect and pathological findings in any thyroid glands.</description><identifier>ISSN: 1344-3941</identifier><identifier>EISSN: 1740-0929</identifier><identifier>DOI: 10.1111/asj.13269</identifier><identifier>PMID: 31309667</identifier><language>eng</language><publisher>Australia: Blackwell Publishing Ltd</publisher><subject>Animals ; Atrophy ; Bovidae ; Cattle ; Cattle Diseases - etiology ; Cattle Diseases - pathology ; Cellular structure ; Epithelium ; Farms ; Fibrosis ; Fukushima ; Fukushima Nuclear Accident ; Glands ; Goiter ; Goiter - pathology ; Goiter - veterinary ; Humans ; Inflammation ; Ionizing radiation ; Japan ; Japanese Black ; Morphology ; Neoplasms, Radiation-Induced - veterinary ; Nuclear accidents ; Nuclear accidents & safety ; Nuclear energy ; Nuclear Power Plants ; Radiation Dosage ; Signs and symptoms ; Thyroid ; Thyroid diseases ; Thyroid gland ; Thyroid Gland - pathology ; Thyroid Gland - physiopathology ; Thyroid Gland - radiation effects ; Thyroid Neoplasms - veterinary</subject><ispartof>Animal science journal, 2019-09, Vol.90 (9), p.1333-1339</ispartof><rights>2019 Japanese Society of Animal Science</rights><rights>2019 Japanese Society of Animal Science.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4439-2f7b1cf8d86affb5478900a4b6e6427c07b68e07b650d74dbba0957f6345fcf93</citedby><cites>FETCH-LOGICAL-c4439-2f7b1cf8d86affb5478900a4b6e6427c07b68e07b650d74dbba0957f6345fcf93</cites><orcidid>0000-0002-3328-0796 ; 0000-0001-8319-3407 ; 0000-0001-5767-8603</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fasj.13269$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fasj.13269$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>315,782,786,1419,27933,27934,45583,45584</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31309667$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sasaki, Jun</creatorcontrib><creatorcontrib>Uehara, Megumi</creatorcontrib><creatorcontrib>Sato, Itaru</creatorcontrib><creatorcontrib>Satoh, Hiroshi</creatorcontrib><creatorcontrib>Deguchi, Yoshitaka</creatorcontrib><creatorcontrib>Chida, Hiroyuki</creatorcontrib><creatorcontrib>Natsuhori, Masahiro</creatorcontrib><creatorcontrib>Murata, Takahisa</creatorcontrib><creatorcontrib>Ochiai, Kenji</creatorcontrib><creatorcontrib>Otani, Kumiko</creatorcontrib><creatorcontrib>Okada, Keiji</creatorcontrib><creatorcontrib>Ito, Nobuhiko</creatorcontrib><title>Pathological characteristics of thyroid glands from Japanese Black Cattle living in the restricted area of the Fukushima Daiichi Nuclear Power Plant accident</title><title>Animal science journal</title><addtitle>Anim Sci J</addtitle><description>To study the effect of ionizing radiation on thyroid glands, 66 Japanese Black cattle residing in the restricted area of the Fukushima Daiichi Nuclear Power Plant in 2013–2017 were pathologically examined. There were no clinical symptoms of thyroid disease in these cattle. Three cases of goiter and seven of atrophy were found in two among the four farms examined. Cases of goiter exhibited normal morphological structure without mass or nodule formation in thyroid glands. Cellular atypia or capsular invasion of the follicular epithelium was absent. The estimated integrated dose of external radiation in goiter cases ranged from maximum 797 mSv to minimum 24 mSv. All lobules in the seven atrophic thyroid glands were affected, but pathological findings, such as inflammatory cell infiltration or stromal fibrosis, were not observed. The estimated integrated dose of external radiation in atrophic thyroids ranged from maximum 589 mSv to minimum 8 mSv. Immunohistochemical analysis of anti‐nitroguanosine and the TUNEL method in goiter and atrophic thyroid glands did not reveal any positive findings. The present study indicates that there was no significant relationship between a radiation effect and pathological findings in any thyroid glands.</description><subject>Animals</subject><subject>Atrophy</subject><subject>Bovidae</subject><subject>Cattle</subject><subject>Cattle Diseases - etiology</subject><subject>Cattle Diseases - pathology</subject><subject>Cellular structure</subject><subject>Epithelium</subject><subject>Farms</subject><subject>Fibrosis</subject><subject>Fukushima</subject><subject>Fukushima Nuclear Accident</subject><subject>Glands</subject><subject>Goiter</subject><subject>Goiter - pathology</subject><subject>Goiter - veterinary</subject><subject>Humans</subject><subject>Inflammation</subject><subject>Ionizing radiation</subject><subject>Japan</subject><subject>Japanese Black</subject><subject>Morphology</subject><subject>Neoplasms, Radiation-Induced - veterinary</subject><subject>Nuclear accidents</subject><subject>Nuclear accidents & safety</subject><subject>Nuclear energy</subject><subject>Nuclear Power Plants</subject><subject>Radiation Dosage</subject><subject>Signs and symptoms</subject><subject>Thyroid</subject><subject>Thyroid diseases</subject><subject>Thyroid gland</subject><subject>Thyroid Gland - pathology</subject><subject>Thyroid Gland - physiopathology</subject><subject>Thyroid Gland - radiation effects</subject><subject>Thyroid Neoplasms - veterinary</subject><issn>1344-3941</issn><issn>1740-0929</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kcFS3SAUhhmnHbW2C1_AYaYrF1EIJISlXqut41hn2q4zJwRuuHLDFYjOfRjftdhYd7I4sPj4zoEfoUNKTmhepxBXJ5SVtdxB-1RwUhBZyg_5zDgvmOR0D32KcUUIFZJUu2iPUUZkXYt99HwHafDOL60Ch9UAAVTSwcZkVcTe4DRsg7c9XjoY-4hN8Gt8DRsYddT43IG6xwtIyWns7KMdl9iO-Y7GQccUbHb1GIKGWaXx5XQ_xcGuAV-AtWqw-HZSTkPAd_5J55rbJAxK2V6P6TP6aMBF_eV1P0B_Lr_9Xnwvbn5e_Vic3RSKcyaL0oiOKtP0TQ3GdBUXjSQEeFfrmpdCEdHVjX6pFekF77sOiKyEqRmvjDKSHaCvs3cT_MOUJ29XfgpjbtmWZcNKTkshMnU8Uyr4GIM27Sbkl4RtS0n7EkSbg2j_BZHZo1fj1K11_0b-__kMnM7Ak3V6-76pPft1PSv_AhJVlH0</recordid><startdate>201909</startdate><enddate>201909</enddate><creator>Sasaki, Jun</creator><creator>Uehara, Megumi</creator><creator>Sato, Itaru</creator><creator>Satoh, Hiroshi</creator><creator>Deguchi, Yoshitaka</creator><creator>Chida, Hiroyuki</creator><creator>Natsuhori, Masahiro</creator><creator>Murata, Takahisa</creator><creator>Ochiai, Kenji</creator><creator>Otani, Kumiko</creator><creator>Okada, Keiji</creator><creator>Ito, Nobuhiko</creator><general>Blackwell Publishing Ltd</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QL</scope><scope>7T7</scope><scope>7TK</scope><scope>7U9</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>H94</scope><scope>M7N</scope><scope>P64</scope><scope>RC3</scope><orcidid>https://orcid.org/0000-0002-3328-0796</orcidid><orcidid>https://orcid.org/0000-0001-8319-3407</orcidid><orcidid>https://orcid.org/0000-0001-5767-8603</orcidid></search><sort><creationdate>201909</creationdate><title>Pathological characteristics of thyroid glands from Japanese Black Cattle living in the restricted area of the Fukushima Daiichi Nuclear Power Plant accident</title><author>Sasaki, Jun ; Uehara, Megumi ; Sato, Itaru ; Satoh, Hiroshi ; Deguchi, Yoshitaka ; Chida, Hiroyuki ; Natsuhori, Masahiro ; Murata, Takahisa ; Ochiai, Kenji ; Otani, Kumiko ; Okada, Keiji ; Ito, Nobuhiko</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4439-2f7b1cf8d86affb5478900a4b6e6427c07b68e07b650d74dbba0957f6345fcf93</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2019</creationdate><topic>Animals</topic><topic>Atrophy</topic><topic>Bovidae</topic><topic>Cattle</topic><topic>Cattle Diseases - etiology</topic><topic>Cattle Diseases - pathology</topic><topic>Cellular structure</topic><topic>Epithelium</topic><topic>Farms</topic><topic>Fibrosis</topic><topic>Fukushima</topic><topic>Fukushima Nuclear Accident</topic><topic>Glands</topic><topic>Goiter</topic><topic>Goiter - pathology</topic><topic>Goiter - veterinary</topic><topic>Humans</topic><topic>Inflammation</topic><topic>Ionizing radiation</topic><topic>Japan</topic><topic>Japanese Black</topic><topic>Morphology</topic><topic>Neoplasms, Radiation-Induced - veterinary</topic><topic>Nuclear accidents</topic><topic>Nuclear accidents & safety</topic><topic>Nuclear energy</topic><topic>Nuclear Power Plants</topic><topic>Radiation Dosage</topic><topic>Signs and symptoms</topic><topic>Thyroid</topic><topic>Thyroid diseases</topic><topic>Thyroid gland</topic><topic>Thyroid Gland - pathology</topic><topic>Thyroid Gland - physiopathology</topic><topic>Thyroid Gland - radiation effects</topic><topic>Thyroid Neoplasms - veterinary</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sasaki, Jun</creatorcontrib><creatorcontrib>Uehara, Megumi</creatorcontrib><creatorcontrib>Sato, Itaru</creatorcontrib><creatorcontrib>Satoh, Hiroshi</creatorcontrib><creatorcontrib>Deguchi, Yoshitaka</creatorcontrib><creatorcontrib>Chida, Hiroyuki</creatorcontrib><creatorcontrib>Natsuhori, Masahiro</creatorcontrib><creatorcontrib>Murata, Takahisa</creatorcontrib><creatorcontrib>Ochiai, Kenji</creatorcontrib><creatorcontrib>Otani, Kumiko</creatorcontrib><creatorcontrib>Okada, Keiji</creatorcontrib><creatorcontrib>Ito, Nobuhiko</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Neurosciences Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>Genetics Abstracts</collection><jtitle>Animal science journal</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sasaki, Jun</au><au>Uehara, Megumi</au><au>Sato, Itaru</au><au>Satoh, Hiroshi</au><au>Deguchi, Yoshitaka</au><au>Chida, Hiroyuki</au><au>Natsuhori, Masahiro</au><au>Murata, Takahisa</au><au>Ochiai, Kenji</au><au>Otani, Kumiko</au><au>Okada, Keiji</au><au>Ito, Nobuhiko</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Pathological characteristics of thyroid glands from Japanese Black Cattle living in the restricted area of the Fukushima Daiichi Nuclear Power Plant accident</atitle><jtitle>Animal science journal</jtitle><addtitle>Anim Sci J</addtitle><date>2019-09</date><risdate>2019</risdate><volume>90</volume><issue>9</issue><spage>1333</spage><epage>1339</epage><pages>1333-1339</pages><issn>1344-3941</issn><eissn>1740-0929</eissn><abstract>To study the effect of ionizing radiation on thyroid glands, 66 Japanese Black cattle residing in the restricted area of the Fukushima Daiichi Nuclear Power Plant in 2013–2017 were pathologically examined. There were no clinical symptoms of thyroid disease in these cattle. Three cases of goiter and seven of atrophy were found in two among the four farms examined. Cases of goiter exhibited normal morphological structure without mass or nodule formation in thyroid glands. Cellular atypia or capsular invasion of the follicular epithelium was absent. The estimated integrated dose of external radiation in goiter cases ranged from maximum 797 mSv to minimum 24 mSv. All lobules in the seven atrophic thyroid glands were affected, but pathological findings, such as inflammatory cell infiltration or stromal fibrosis, were not observed. The estimated integrated dose of external radiation in atrophic thyroids ranged from maximum 589 mSv to minimum 8 mSv. Immunohistochemical analysis of anti‐nitroguanosine and the TUNEL method in goiter and atrophic thyroid glands did not reveal any positive findings. The present study indicates that there was no significant relationship between a radiation effect and pathological findings in any thyroid glands.</abstract><cop>Australia</cop><pub>Blackwell Publishing Ltd</pub><pmid>31309667</pmid><doi>10.1111/asj.13269</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-3328-0796</orcidid><orcidid>https://orcid.org/0000-0001-8319-3407</orcidid><orcidid>https://orcid.org/0000-0001-5767-8603</orcidid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1344-3941 |
| ispartof | Animal science journal, 2019-09, Vol.90 (9), p.1333-1339 |
| issn | 1344-3941 1740-0929 |
| language | eng |
| recordid | cdi_proquest_journals_2283241277 |
| source | Access via Wiley Online Library; MEDLINE; Alma/SFX Local Collection |
| subjects | Animals Atrophy Bovidae Cattle Cattle Diseases - etiology Cattle Diseases - pathology Cellular structure Epithelium Farms Fibrosis Fukushima Fukushima Nuclear Accident Glands Goiter Goiter - pathology Goiter - veterinary Humans Inflammation Ionizing radiation Japan Japanese Black Morphology Neoplasms, Radiation-Induced - veterinary Nuclear accidents Nuclear accidents & safety Nuclear energy Nuclear Power Plants Radiation Dosage Signs and symptoms Thyroid Thyroid diseases Thyroid gland Thyroid Gland - pathology Thyroid Gland - physiopathology Thyroid Gland - radiation effects Thyroid Neoplasms - veterinary |
| title | Pathological characteristics of thyroid glands from Japanese Black Cattle living in the restricted area of the Fukushima Daiichi Nuclear Power Plant accident |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-11-29T10%3A32%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Pathological%20characteristics%20of%20thyroid%20glands%20from%20Japanese%20Black%20Cattle%20living%20in%20the%20restricted%20area%20of%20the%20Fukushima%20Daiichi%20Nuclear%20Power%20Plant%20accident&rft.jtitle=Animal%20science%20journal&rft.au=Sasaki,%20Jun&rft.date=2019-09&rft.volume=90&rft.issue=9&rft.spage=1333&rft.epage=1339&rft.pages=1333-1339&rft.issn=1344-3941&rft.eissn=1740-0929&rft_id=info:doi/10.1111/asj.13269&rft_dat=%3Cproquest_cross%3E2283241277%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2283241277&rft_id=info:pmid/31309667&rfr_iscdi=true |