Sodium valproate in psychiatric practice: time for a change in perception

Sodium valproate and related preparations have recently undergone regulatory review following concern about effects on the unborn child and doctors' failure to communicate risk. The issues are wider. Valproate is overused in psychiatry based on the false perception that ‘ease’ of use equates to...

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Veröffentlicht in:British journal of psychiatry 2019-09, Vol.215 (3), p.516-518
1. Verfasser: Owens, David Cunningham
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description Sodium valproate and related preparations have recently undergone regulatory review following concern about effects on the unborn child and doctors' failure to communicate risk. The issues are wider. Valproate is overused in psychiatry based on the false perception that ‘ease’ of use equates to better safety than alternatives. Valproic acid can disrupt fundamental physiological processes, the consequences of which are poorly understood and little discussed in the psychiatric literature. Valproate may be useful in a small number of patients with bipolar disorder but current prescribing patterns are unjustified. Perception needs to change.
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source Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Cambridge Journals; Applied Social Sciences Index & Abstracts (ASSIA); Alma/SFX Local Collection
subjects Advisory groups
Autism
Babies
Bipolar disorder
Birth control
Birth defects
Childbearing
Drug dosages
Drugs
Editorial
Epilepsy
Lithium
Perception
Physicians
Physiological processes
Polycystic ovary syndrome
Pregnancy
Prescribing
Psychiatric services
Psychiatry
Psychotropic drugs
Sodium
Sodium valproate
Systematic review
Valproic acid
Womens health
title Sodium valproate in psychiatric practice: time for a change in perception
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