Toward Understanding Kernicterus: A Challenge to Improve the Management of Jaundiced Newborns

We sought to evaluate the sensitivity and specificity of total serum bilirubin concentration (TSB) and free (unbound) bilirubin concentration (Bf) as predictors of risk for bilirubin toxicity and kernicterus and to examine consistency between these findings and proposed mechanisms of bilirubin trans...

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Veröffentlicht in:	Pediatrics (Evanston) 2006-02, Vol.117 (2), p.474-485
Hauptverfasser:	Wennberg, Richard P, Ahlfors, Charles E, Bhutani, Vinod K, Johnson, Lois H, Shapiro, Steven M
Format:	Artikel
Sprache:	eng
Schlagworte:	Babies Bile Bilirubin - blood Bilirubin - metabolism Blood-Brain Barrier Brain Brain - metabolism Care and treatment Health aspects Humans Hyperbilirubinemia, Neonatal - complications Hyperbilirubinemia, Neonatal - physiopathology Hyperbilirubinemia, Neonatal - therapy Infant, Newborn Infants Jaundice, Neonatal - complications Jaundice, Neonatal - diagnosis Kernicterus Kernicterus - blood Kernicterus - etiology Kernicterus - physiopathology Kernicterus - prevention & control Medical disorders Pediatrics Risk Assessment Risk factors Sensitivity Sensitivity and Specificity Serum Albumin - analysis Toxicity
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