Palonosetron: In the Prevention of Nausea and Vomiting

Summary Palonosetron is a second-generation serotonin 5-HT 3 receptor antagonist, with a distinct pharmacological profile that differs from first-generation 5-HT 3 receptor antagonists. Intravenous palonosetron is widely indicated for the prevention of chemotherapy-induced nausea and vomiting (CINV)...

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Veröffentlicht in:	Drugs (New York, N.Y.) N.Y.), 2009-11, Vol.69 (16), p.2257-2278
Hauptverfasser:	Yang, Lily P. H., Scott, Lesley J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adis Drug Evaluation Antiemetics - adverse effects Antiemetics - pharmacokinetics Antiemetics - therapeutic use Antineoplastic Agents - adverse effects Biological and medical sciences Cytochrome P-450 Digestive system Drug Interactions Health aspects Humans Internal Medicine Isoquinolines - adverse effects Isoquinolines - pharmacokinetics Isoquinolines - therapeutic use Medical sciences Medicine Medicine & Public Health Nausea - chemically induced Nausea - prevention & control Palonosetron Pharmacogenetics Pharmacokinetics Pharmacology. Drug treatments Pharmacology/Toxicology Pharmacotherapy Physiological aspects Postoperative Nausea and Vomiting - prevention & control Quinuclidines - adverse effects Quinuclidines - pharmacokinetics Quinuclidines - therapeutic use Serotonin Antagonists - adverse effects Serotonin Antagonists - pharmacokinetics Serotonin Antagonists - therapeutic use Tumors Vomiting - chemically induced Vomiting - prevention & control
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