Phenotypic Profiling of Circulating Tumor Cells in Metastatic Prostate Cancer Patients Using Nanoparticle-Mediated Ranking

The analysis of circulating tumor cells (CTCs) provides a means to collect information about the evolving properties of a tumor during cancer progression and treatment. For patients with metastatic prostate cancer, noninvasive serial measurements of bloodborne cells may provide a means to tailor the...

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Veröffentlicht in:	Analytical chemistry (Washington) 2019-08, Vol.91 (15), p.9348-9355
Hauptverfasser:	Green, Brenda J, Nguyen, Vivian, Atenafu, Eshetu, Weeber, Phillip, Duong, Bill T. V, Thiagalingam, Punithan, Labib, Mahmoud, Mohamadi, Reza M, Hansen, Aaron R, Joshua, Anthony M, Kelley, Shana O
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgen receptors Androstenes - therapeutic use Antibodies Antigens Antineoplastic Agents, Immunological - therapeutic use Cadherins Cadherins - analysis Cadherins - immunology Cell adhesion Cell adhesion & migration Cell adhesion molecules Chemistry Disease Progression Epithelial Cell Adhesion Molecule - immunology Epithelial cells Humans Magnetite Nanoparticles - chemistry Magnetite Nanoparticles - therapeutic use Male Mesenchyme Metastases Metastasis Microfluidic devices Microfluidics N-Cadherin Nanoparticles Neoplastic Cells, Circulating - pathology Phenotype Phenotypes Phenylthiohydantoin - analogs & derivatives Phenylthiohydantoin - therapeutic use Prostate cancer Prostatic Neoplasms - drug therapy Prostatic Neoplasms - pathology Receptors, Androgen - analysis Receptors, Androgen - immunology Sensitivity Tumor cells Tumors
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