Oleuropein modulates glioblastoma miRNA pattern different from Olea europaea leaf extract

Glioblastoma (GBM) is the most prevalent and deadliest subtype of glioma. Despite current innovations in existing therapeutic modalities, GBM remains incurable, and alternative therapies are required. Previously, we demonstrated that Olea europaea leaf extract (OLE) kills GBM cells by modulating miR...

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Veröffentlicht in:	Human & experimental toxicology 2019-09, Vol.38 (9), p.1102-1110
Hauptverfasser:	Tezcan, G, Aksoy, SA, Tunca, B, Bekar, A, Mutlu, M, Cecener, G, Egeli, U, Kocaeli, H, Demirci, H, Taskapilioglu, MO
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antineoplastic Agents, Alkylating - pharmacology Antineoplastic Agents, Phytogenic - pharmacology Antitumor activity Biotechnology Brain cancer Brain Neoplasms - genetics Cell Line, Tumor Cell Proliferation - drug effects Cell Survival - drug effects Glioblastoma Glioblastoma - genetics Glioma Humans Innovations Iridoids - pharmacology Leaves Medical innovations MicroRNAs miRNA Olea Olea europaea Oleuropein Plant extracts Plant Extracts - pharmacology Plant Leaves Polymerase chain reaction Reverse transcription Ribonucleic acid RNA Temozolomide Temozolomide - pharmacology Variance analysis
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