Preoperative FLAC/granulocyte-colony-stimulating factor chemotherapy for stage II breast cancer: a prospective randomized trial

Preoperative chemotherapy for stage II breast cancer may reduce locoregional tumors and provides initial treatment for systemic micrometastases. We conducted a prospective, randomized trial to evaluate the ability of intensive preoperative chemotherapy to enhance the outcome of this approach. Patien...

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Veröffentlicht in:	Annals of surgical oncology 2003-07, Vol.10 (6), p.635, Article 635
Hauptverfasser:	Danforth, Jr, David N, Cowan, Kenneth, Altemus, Rosemary, Merino, Maria, Chow, Catherine, Berman, Arlene, Chaudhry, Usha, Shriver, Craig, Steinberg, Seth M, Zujewski, JoAnne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Combined Chemotherapy Protocols - administration & dosage Antineoplastic Combined Chemotherapy Protocols - therapeutic use Breast Neoplasms - drug therapy Breast Neoplasms - pathology Breast Neoplasms - surgery Combined Modality Therapy Cyclophosphamide - administration & dosage Disease-Free Survival Doxorubicin - administration & dosage Female Fluorouracil - administration & dosage Granulocyte Colony-Stimulating Factor - administration & dosage Granulocyte-Macrophage Colony-Stimulating Factor - administration & dosage Humans Infusions, Intravenous Injections, Intravenous Injections, Subcutaneous Leucovorin - administration & dosage Mastectomy Mastectomy, Segmental Middle Aged Neoadjuvant Therapy Prognosis Radiotherapy, Adjuvant Treatment Outcome
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