Randomized phase III trial of gastrectomy with or without neoadjuvant S-1 plus cisplatin for type 4 or large type 3 gastric cancer, the short-term safety and surgical results: Japan Clinical Oncology Group Study (JCOG0501)

Background The prognosis of patients with linitis plastica (type 4) and large (≥ 8 cm) ulcero-invasive-type (type 3) gastric cancer is extremely poor, even after extended surgery and adjuvant chemotherapy. Given the promising results of our previous phase II study evaluating neoadjuvant chemotherapy...

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Veröffentlicht in:	Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 2019-09, Vol.22 (5), p.1044-1052
Hauptverfasser:	Terashima, Masanori, Iwasaki, Yoshiaki, Mizusawa, Junki, Katayama, Hiroshi, Nakamura, Kenichi, Katai, Hitoshi, Yoshikawa, Takaki, Ito, Yuichi, Kaji, Masahide, Kimura, Yutaka, Hirao, Motohiro, Yamada, Makoto, Kurita, Akira, Takagi, Masakazu, Boku, Narikazu, Sano, Takeshi, Sasako, Mitsuru
Format:	Artikel
Sprache:	eng
Schlagworte:	Abdominal Surgery Adult Aged Antineoplastic Combined Chemotherapy Protocols - therapeutic use Cancer Research Chemotherapy Cisplatin Cisplatin - administration & dosage Clinical trials Combined Modality Therapy Diarrhea Drug Combinations Female Follow-Up Studies Gastrectomy Gastrectomy - mortality Gastric cancer Gastroenterology Humans Invasiveness Male Medical prognosis Medicine Medicine & Public Health Middle Aged Morbidity Mortality Nausea Neoadjuvant Therapy - mortality Neoplasm Staging Neutropenia Oncology Original Article Oxonic Acid - administration & dosage Patients Peritoneal Neoplasms - secondary Peritoneal Neoplasms - therapy Stomach Neoplasms - pathology Stomach Neoplasms - therapy Surgery Surgical Oncology Survival Rate Tegafur - administration & dosage Young Adult
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