Transferrin ensures survival of ovarian carcinoma cells when apoptosis is induced by TNF[alpha], FasL, TRAIL, or Myc

The activation of Myc induces apoptosis of human ovarian adenocarcinoma N.1 cells when serum factors are limited. However, the downstream mechanism that is triggered by Myc is unknown. Myc-activation and treatment with the proapoptotic ligands TNFalpha, FasL, and TRAIL induced H-ferritin expression...

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Veröffentlicht in:	Oncogene 2003-11, Vol.22 (51), p.8343
Hauptverfasser:	Fassl, Sandra, Leisser, Christina, Huettenbrenner, Simone, Maier, Susanne, Rosenberger, Georg, Strasser, Stephan, Grusch, Michael, Fuhrmann, Gerhard, Leuhuber, Katharina, Polgar, Doris, Stani, Josefine, Tichy, Brigitte, Nowotny, Christine, Krupitza, Georg
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer Cytotoxicity Homeostasis Ovaries
Online-Zugang:	Volltext
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