The function of multiple I[kappa]B : NF-[kappa]B complexes in the resistance of cancer cells to Taxol-induced apoptosis

The Rel/NF-kappaB transcription factors play a key role in the regulation of apoptosis and in tumorigenesis by controlling the expressions of specific genes. To determine the role of the constitutive activity of RelA in tumorigenesis, we generated pancreatic tumor cell lines that express a dominant...

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Veröffentlicht in:	Oncogene 2002-09, Vol.21 (42), p.6510
Hauptverfasser:	Dong, Qiang G, Sclabas, Guido M, Fujioka, Shuichi, Schmidt, Christian, Peng, Bailu, Wu, TianAi, Tsao, Ming-Sound, Evans, Douglas B, Abbruzzese, James L, McDonnell, Timothy J, Chiao, Paul J
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Cancer Genes Kinases Oncology Phosphorylation Proteins Signal transduction Tumorigenesis Tumors
Online-Zugang:	Volltext
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