Pharmacokinetics, Safety, and Tolerability Evaluation of Single and Multiple Doses of GSK3342830 in Healthy Volunteers

This was a first‐time‐in‐human randomized, double‐blind, single‐center, placebo‐controlled dose‐escalation study to determine the safety, tolerability, and pharmacokinetic (PK) profiles of GSK3342830 after single and repeat intravenous doses in healthy adult subjects (NCT0271424). Sixty‐two subjects...

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Veröffentlicht in:	Clinical pharmacology in drug development 2019-08, Vol.8 (6), p.754-764
Hauptverfasser:	Tenero, David, Farinola, Nicholas, Berkowitz, Elchonon M., Tiffany, Courtney A., Qian, Yanwen, Xue, Zhengyu, Raychaudhuri, Aparna, Gardiner, David F.
Format:	Artikel
Sprache:	eng
Schlagworte:	antibiotic Antibiotics cephalosporin Clinical trials Drug dosages Drug therapy Pharmacokinetics Pharmacology siderophore
Online-Zugang:	Volltext
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