Complex TNF-α B cell epitope MAP vaccine alleviates murine ulcerative colitis

The present study aimed to develop a tumor necrosis factor‑α (TNF‑α) B‑cell epitope/IL‑1β helper T lymphocyte epitope complex MAP vaccine for the alleviation of ulcerative colitis (UC) in mice. The B cell epitopes of murine TNF‑α (mTNF‑α) were predicted in silico and coupled with the universal inter...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of molecular medicine 2019-09, Vol.44 (3), p.1106-1116
Hauptverfasser:	Sun, Yan, Pan, Wensheng, Zhang, Jun, Cui, Ying, Wang, Huiju, Ru, Guoqing, Chen, Legao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens B-Lymphocytes - immunology B-Lymphocytes - metabolism Biological activity Colitis, Ulcerative - etiology Colitis, Ulcerative - metabolism Colitis, Ulcerative - pathology Disease Disease Models, Animal Drug dosages Epitopes, B-Lymphocyte - immunology Immunization Immunoglobulins Inflammatory bowel disease Intercellular Signaling Peptides and Proteins - immunology Intestinal Mucosa - immunology Intestinal Mucosa - metabolism Intestinal Mucosa - pathology Laboratory animals Mice Peptides Permeability Protein Binding Proteins Studies Tumor Necrosis Factor-alpha - metabolism Tumor necrosis factor-TNF Vaccines Vaccines - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!