Epigallocatechin gallate attenuates arsenic induced genotoxicity via regulation of oxidative stress in balb/C mice

Arsenic is well known genotoxicant which causes the excessive generation of reactive oxygen species (ROS) and inhibition of antioxidant enzyme systems leading to cell damage through the activation of oxidative sensitive signaling pathways. Epigallocatechin gallate (EGCG), the main and active polyphe...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular biology reports 2019-10, Vol.46 (5), p.5355-5369
Hauptverfasser:	Kaushal, Surbhi, Ahsan, Aitizaz Ul, Sharma, Vijay Lakshmi, Chopra, Mani
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal Anatomy Animal Biochemistry Animals Antioxidants Antioxidants - metabolism Apoptosis - drug effects Arsenic Arsenic - adverse effects Arsenic - toxicity Arsenic Poisoning - drug therapy Biomedical and Life Sciences Bone marrow Catechin Catechin - analogs & derivatives Catechin - metabolism Catechin - pharmacology Cell activation Chromosome aberrations DNA Damage - drug effects DNA fragmentation Epigallocatechin gallate Female Free radicals Genotoxicity Green tea Histology Intoxication Kidneys Life Sciences Lipid peroxidation Lymphocytes Mice Mice, Inbred BALB C Morphology Mutagenicity Tests - methods Original Article Oxidative stress Oxidative Stress - drug effects Reactive oxygen species Reactive Oxygen Species - metabolism Signal Transduction - drug effects
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!