Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging
We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healt...
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Veröffentlicht in: | Journal of infrared, millimeter and terahertz waves millimeter and terahertz waves, 2019-02, Vol.40 (2), p.247-256 |
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container_title | Journal of infrared, millimeter and terahertz waves |
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creator | Ji, Young Bin Kim, Jung Min Lee, Young Han Choi, Yuna Kim, Da Hee Huh, Yong-Min Oh, Seung Jae Koh, Yoon Woo Suh, Jin-Suck |
description | We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal. |
doi_str_mv | 10.1007/s10762-018-0562-7 |
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Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal.</description><identifier>ISSN: 1866-6892</identifier><identifier>EISSN: 1866-6906</identifier><identifier>DOI: 10.1007/s10762-018-0562-7</identifier><language>eng</language><publisher>New York: Springer US</publisher><subject>Absorptivity ; Classical Electrodynamics ; Electrical Engineering ; Electronics and Microelectronics ; Engineering ; Instrumentation ; Keratin ; Moisture content ; Refractivity ; Signal reflection ; Tongue ; Tumors</subject><ispartof>Journal of infrared, millimeter and terahertz waves, 2019-02, Vol.40 (2), p.247-256</ispartof><rights>Springer Science+Business Media, LLC, part of Springer Nature 2019</rights><rights>Copyright Springer Science & Business Media 2019</rights><rights>Journal of Infrared, Millimeter, and Terahertz Waves is a copyright of Springer, (2019). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c344t-e641f42b0c43e3bc8476bb44a5199237c62aedccc7cac51c2a4b9cc271802d393</citedby><cites>FETCH-LOGICAL-c344t-e641f42b0c43e3bc8476bb44a5199237c62aedccc7cac51c2a4b9cc271802d393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10762-018-0562-7$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10762-018-0562-7$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Ji, Young Bin</creatorcontrib><creatorcontrib>Kim, Jung Min</creatorcontrib><creatorcontrib>Lee, Young Han</creatorcontrib><creatorcontrib>Choi, Yuna</creatorcontrib><creatorcontrib>Kim, Da Hee</creatorcontrib><creatorcontrib>Huh, Yong-Min</creatorcontrib><creatorcontrib>Oh, Seung Jae</creatorcontrib><creatorcontrib>Koh, Yoon Woo</creatorcontrib><creatorcontrib>Suh, Jin-Suck</creatorcontrib><title>Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging</title><title>Journal of infrared, millimeter and terahertz waves</title><addtitle>J Infrared Milli Terahz Waves</addtitle><description>We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal.</description><subject>Absorptivity</subject><subject>Classical Electrodynamics</subject><subject>Electrical Engineering</subject><subject>Electronics and Microelectronics</subject><subject>Engineering</subject><subject>Instrumentation</subject><subject>Keratin</subject><subject>Moisture content</subject><subject>Refractivity</subject><subject>Signal reflection</subject><subject>Tongue</subject><subject>Tumors</subject><issn>1866-6892</issn><issn>1866-6906</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2019</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNp9kE1PwyAAhonRxDn9Ad5IPFeBUihH0_ixaGKi25lQRrsuLWzQmrhfL7UaT3riTXjel_AAcInRNUaI3wSMOCMJwnmCshj4EZjhnLGECcSOf3IuyCk4C2GLEKNUsBmoFvbdhL6pVd84C10Fn4yP2TaHxtbwbT-ozg0BFqZtYaG8bqzr1Mj1GwOXztaDgaswsstY3BjfH-CrqVqjvwYXnarj5Tk4qVQbzMX3OQer-7tl8Zg8vzwsitvnRKeU9olhFFeUlEjT1KSlzilnZUmpyrAQJOWaEWXWWmuulc6wJoqWQmvCcY7IOhXpHFxNuzvv9kP8mNy6wdv4pCQkE5znFGf_UjgKQynNUaTwRGnvQvCmkjvfdMp_SIzkKF1O0mWULkfpkscOmTohsrY2_nf579InWc2Erw</recordid><startdate>20190201</startdate><enddate>20190201</enddate><creator>Ji, Young Bin</creator><creator>Kim, Jung Min</creator><creator>Lee, Young Han</creator><creator>Choi, Yuna</creator><creator>Kim, Da Hee</creator><creator>Huh, Yong-Min</creator><creator>Oh, Seung Jae</creator><creator>Koh, Yoon Woo</creator><creator>Suh, Jin-Suck</creator><general>Springer US</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope><scope>8FE</scope><scope>8FG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>HCIFZ</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope></search><sort><creationdate>20190201</creationdate><title>Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging</title><author>Ji, Young Bin ; 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Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal.</abstract><cop>New York</cop><pub>Springer US</pub><doi>10.1007/s10762-018-0562-7</doi><tpages>10</tpages></addata></record> |
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subjects | Absorptivity Classical Electrodynamics Electrical Engineering Electronics and Microelectronics Engineering Instrumentation Keratin Moisture content Refractivity Signal reflection Tongue Tumors |
title | Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging |
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