Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging

We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healt...

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Veröffentlicht in:Journal of infrared, millimeter and terahertz waves millimeter and terahertz waves, 2019-02, Vol.40 (2), p.247-256
Hauptverfasser: Ji, Young Bin, Kim, Jung Min, Lee, Young Han, Choi, Yuna, Kim, Da Hee, Huh, Yong-Min, Oh, Seung Jae, Koh, Yoon Woo, Suh, Jin-Suck
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container_issue 2
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container_title Journal of infrared, millimeter and terahertz waves
container_volume 40
creator Ji, Young Bin
Kim, Jung Min
Lee, Young Han
Choi, Yuna
Kim, Da Hee
Huh, Yong-Min
Oh, Seung Jae
Koh, Yoon Woo
Suh, Jin-Suck
description We investigated the feasibility of using terahertz (THz) reflection imaging to detect keratinizing squamous cell carcinoma (SCC) of the tongue. Four fresh keratinizing SCC tissues were studied, which had been surgically resected. All of the keratinizing SCCs were well distinguished from normal healthy tissues. We showed that the tumor regions exhibited low THz reflection despite having higher water content than normal regions. The refractive indices and absorption coefficients were low in the tumor tissues despite the relatively high water content. Our results showed that there were dominant factors such as keratin pearls, other than the water content affecting the THz reflection signal.
doi_str_mv 10.1007/s10762-018-0562-7
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subjects Absorptivity
Classical Electrodynamics
Electrical Engineering
Electronics and Microelectronics
Engineering
Instrumentation
Keratin
Moisture content
Refractivity
Signal reflection
Tongue
Tumors
title Investigation of Keratinizing Squamous Cell Carcinoma of the Tongue Using Terahertz Reflection Imaging
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