Pharmacological Effects of a Specific Leukotriene B4 Receptor Antagonist (VML 295) on Blood Leukocytes, Cutaneous Inflammation and Epidermal Proliferation

VML 295 (LY 293111) is a potent and specific leukotriene 4 receptor antagonist. It has previously been shown in human volunteers that VML 295 at a dosage of 48 mg twice daily inhibits the ex vivo leukotriene B 4 (LTB 4 )-induced upregulation of CD11b on peripheral blood neutrophils. A clear dose-res...

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Veröffentlicht in:Skin pharmacology and physiology 2000-03, Vol.13 (2), p.75-85
Hauptverfasser: Seegers, Bianca A.M.P.A., Andriessen, Monique P.M., van Hooijdonk, Candida A.E.M., de Bakker, Els S.M., van Vlijmen-Willems, Ivonne M.J.J., Parker, Gerry L., van Erp, Piet E.J., van de Kerkhof, Peter C.M.
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Sprache:eng
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