EEMCO Guidance for the Efficacy Assessment of Antiperspirants and Deodorants

Overproduction of sweat, sweaty skin and body odours are unpleasant for many social groups. Body cleansing products are designed to combat these undesirable features of skin. In addition, antiperspirant and deodorant products are more specifically used in the underarm site by a large part of the adu...

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Veröffentlicht in:Skin pharmacology and applied skin physiology 2003-09, Vol.16 (5), p.324-342
Hauptverfasser: Piérard, G.E., Elsner, P., Marks, R., Masson, P., Paye, M.
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container_end_page 342
container_issue 5
container_start_page 324
container_title Skin pharmacology and applied skin physiology
container_volume 16
creator Piérard, G.E.
Elsner, P.
Marks, R.
Masson, P.
Paye, M.
description Overproduction of sweat, sweaty skin and body odours are unpleasant for many social groups. Body cleansing products are designed to combat these undesirable features of skin. In addition, antiperspirant and deodorant products are more specifically used in the underarm site by a large part of the adult population. Antiperspirants are offered to control emotionally triggered sweating in the armpit. Deodorants are designed to combat malodour generated from bacteria-modified sweat. This review summarizes the physiology of eccrine, apocrine and apoeccrine sweat glands. The mechanisms of action of antiperspirants and deodorants are described as well as the factors influencing their efficacies. A series of tests using various measurement methods can be used to demonstrate the efficacy of antiperspirants. These include the gravimetric method, water evaporation quantification, electrodermal measurements, staining procedures, dye injections and cyanoacrylate skin surface strippings and casting replicas. Deodorant efficacy can be evaluated by sensory assessments performed by an expert panel. Indirect support is provided by visualization of apocrine gland excretion and collection of sweat and volatile compounds. Microbiological assessments and chromatographic analysis also provide indirect information.
doi_str_mv 10.1159/000072072
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subjects Apocrine Glands - secretion
Biological and medical sciences
Clinical Trials as Topic - legislation & jurisprudence
Clinical Trials as Topic - methods
Clinical Trials as Topic/legislation & jurisprudence/methods
Deodorants - adverse effects
Deodorants - pharmacology
Deodorants/adverse effects/pharmacology
Dermatologie
Dermatology
Diseases of the skin. Cosmetics
Eccrine Glands - secretion
EEMCO Review
Human health sciences
Humans
Medical sciences
Practice Guidelines as Topic
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Sciences de la santé humaine
Sweat - secretion
Sweating - drug effects
title EEMCO Guidance for the Efficacy Assessment of Antiperspirants and Deodorants
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