A Fluorescent Flavonoid for Lysosome Imaging: the Effect of Substituents on Selectivity and Optical Properties

Lysosome selective bright orange-red emitting flavonoid ( 2 ) was synthesized by attaching a strong donor (NPh 2 ) group into flavonoid skeleton. As a result of efficient intra molecular charge transfer due to the strong donor group, a significant bathochromic shift was observed from the emission of...

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Veröffentlicht in:	Journal of fluorescence 2019-05, Vol.29 (3), p.599-607
Hauptverfasser:	Bertman, Keti Assor, Abeywickrama, Chathura S., Ingle, Ashley, Shriver, Leah P., Konopka, Michael, Pang, Yi
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical Chemistry Biochemistry Biocompatibility Biological and Medical Physics Biomedical and Life Sciences Biomedicine Biophysics Biotechnology Cell Line Cell Survival Charge transfer Elevation Emission analysis Flavonoids Flavonoids - chemistry Flavonoids - metabolism Fluorescence Fluorescent Dyes - chemistry Fluorescent Dyes - metabolism Humans Localization Lysosomes Lysosomes - metabolism Optical Imaging - methods Optical Phenomena Optical properties Original Article Selectivity Spectrum analysis Temperature Toxicity
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