Injection of the 5-HT2C Receptor Agonist Ro60-0175 into the Ventral Tegmental Area Reduces Cocaine-Induced Locomotor Activity and Cocaine Self-Administration

Previously, we have shown that systemic administration of the 5-HT 2C receptor agonist Ro60-0175 reduces cocaine-induced locomotor activity and cocaine self-administration. Ro60-0175 also alters the activity of midbrain dopamine (DA) neurons of the ventral tegmental area (VTA), a region where 5-HT 2...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2004-02, Vol.29 (2), p.308-318
Hauptverfasser:	Fletcher, Paul J, Chintoh, Araba F, Sinyard, Judy, Higgins, Guy A
Format:	Artikel
Sprache:	eng
Schlagworte:	Aminopyridines - pharmacology Animals Behavior, Animal Behavioral Sciences Biological and medical sciences Biological Psychology Cocaine - administration & dosage Cocaine - pharmacology Conditioning, Operant - drug effects Dose-Response Relationship, Drug Drug Administration Schedule Drug Combinations Drug Interactions Ethylamines - pharmacology Fundamental and applied biological sciences. Psychology Indoles - pharmacology Male Medical sciences Medicine Medicine & Public Health Motor Activity - drug effects Neuropharmacology Neurosciences original-article Pharmacology. Drug treatments Pharmacotherapy Psychiatry Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Rats Rats, Sprague-Dawley Reaction Time - drug effects Reinforcement Schedule Self Administration Serotonin 5-HT2 Receptor Antagonists Time Factors Ventral Tegmental Area - anatomy & histology Ventral Tegmental Area - drug effects
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