The Influence of Mecamylamine on Trigeminal and Olfactory Chemoreception of Nicotine

Nicotine presented to the nasal cavity at low concentrations evokes 'odorous' sensations, and at higher concentrations 'burning' and 'stinging' sensations. A study in smokers and nonsmokers provided evidence of a relationship between the experience with the pharmacologi...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2006-02, Vol.31 (2), p.450-461
Hauptverfasser:	THUERAUF, Norbert, MARKOVIC, Katrin, BRAUN, Georg, BLEICH, Stefan, REULBACH, Udo, KORNHUBER, Johannes, LUNKENHEIMER, Jens
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Chemoreceptor Cells - drug effects Cross-Over Studies Dose-Response Relationship, Drug Double-Blind Method Drug Interactions Evoked Potentials - drug effects Evoked Potentials - physiology Humans Mecamylamine - administration & dosage Medical sciences Middle Aged Multivariate Analysis Nicotine - administration & dosage Nicotinic Antagonists - administration & dosage Olfactory Mucosa - drug effects Olfactory Mucosa - physiology Pain Measurement - methods Sensory Thresholds - drug effects Stereoisomerism Stimulation, Chemical Trigeminal Nerve - drug effects Trigeminal Nerve - physiology
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