Adolescent Rats Find Repeated [Delta]9-THC Less Aversive Than Adult Rats but Display Greater Residual Cognitive Deficits and Changes in Hippocampal Protein Expression Following Exposure

The current study examined whether adolescent rats are more vulnerable than adult rats to the lasting adverse effects of cannabinoid exposure on brain and behavior. Male Wistar rats were repeatedly exposed to Delta-9-tetrahydrocannabinol (Delta(9)-THC, 5 mg/kg i.p.) in a place-conditioning paradigm...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2008-04, Vol.33 (5), p.1113
Hauptverfasser:	Quinn, Heidi R, Matsumoto, Izuru, Callaghan, Paul D, Long, Leonora E, Arnold, Jonathon C, Gunasekaran, Nathan, Thompson, Murray R, Dawson, Bronwyn, Mallet, Paul E, Kashem, Mohammed A, Matsuda-Matsumoto, Haruka, Iwazaki, Takeshi, McGregor, Iain S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adults Child development Gene expression Laboratories Marijuana Memory Protein expression Proteins Proteomics Social interaction Tetrahydrocannabinol THC
Online-Zugang:	Volltext
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