Synthesis of Hexahydrospiroquinoline‐4,1′‐pyrroloquinoline‐2′,5(1H,4′H)‐diones] from 5,6‐dihydro‐4H‐pyrroloquinoline‐1,2‐dione Using Fe3O4@Cu(OH)x as a Nanocatalyst

The tricyclic isatin, 5,6‐dihydro‐4H‐pyrrolo[3,2,1‐ij]quinoline‐1,2‐dione, undergoes three‐component, one‐pot reactions with 1‐aryl‐3‐methylpyrazole‐5‐amines and cyclohexane‐1,3‐diones producing hexacyclic spiro products, hexahydrospiro[pyrazolo[3,4‐b]quinoline‐4,1‐pyrrolo[3,2,1‐ij]quinoline‐2′,5(1H...

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Veröffentlicht in:Journal of heterocyclic chemistry 2019-07, Vol.56 (7), p.1999-2007
Hauptverfasser: Baradarani, Mehdi M, Bahman Ebrahimi Saatluo, Ghabeli, Shiva, Shokri, Zahra, Shahbazi, Masoumeh, Joule, John A
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container_end_page 2007
container_issue 7
container_start_page 1999
container_title Journal of heterocyclic chemistry
container_volume 56
creator Baradarani, Mehdi M
Bahman Ebrahimi Saatluo
Ghabeli, Shiva
Shokri, Zahra
Shahbazi, Masoumeh
Joule, John A
description The tricyclic isatin, 5,6‐dihydro‐4H‐pyrrolo[3,2,1‐ij]quinoline‐1,2‐dione, undergoes three‐component, one‐pot reactions with 1‐aryl‐3‐methylpyrazole‐5‐amines and cyclohexane‐1,3‐diones producing hexacyclic spiro products, hexahydrospiro[pyrazolo[3,4‐b]quinoline‐4,1‐pyrrolo[3,2,1‐ij]quinoline‐2′,5(1H,4′H)‐diones]. Comparable spiro condensation products are also obtained using 4‐hydroxy‐2H‐1‐benzopyran‐2‐one in place of cyclohexane‐1,3‐diones.
doi_str_mv 10.1002/jhet.3579
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source Wiley-Blackwell Journals
subjects Amines
Aromatic compounds
Condensates
Cyclohexane
Iron oxides
Quinoline
title Synthesis of Hexahydrospiroquinoline‐4,1′‐pyrroloquinoline‐2′,5(1H,4′H)‐diones] from 5,6‐dihydro‐4H‐pyrroloquinoline‐1,2‐dione Using Fe3O4@Cu(OH)x as a Nanocatalyst
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