Synthesis of Some Substituted Pyrazolopyrimidine Derivatives: An Environmentally Benign Approach
Pyrazolopyrimidines constitute a medicinally important class of heterocyclic compounds. Herein, we report an efficient and environmentally benign method for the synthesis of pyrazolo[3,4‐d]pyrimidin‐3‐ones from 2,4‐dinitrophenylhydrazine and diethyl malonate under microwave irradiation in 1,3‐dibuty...
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| Veröffentlicht in: | Journal of heterocyclic chemistry 2019-07, Vol.56 (7), p.2056-2062 |
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| container_issue | 7 |
| container_start_page | 2056 |
| container_title | Journal of heterocyclic chemistry |
| container_volume | 56 |
| creator | Pathak, Arpit Kumar Gupta, Sharoni Punjabi, Pinki B. Ameta, Garima Ameta, Chetna |
| description | Pyrazolopyrimidines constitute a medicinally important class of heterocyclic compounds. Herein, we report an efficient and environmentally benign method for the synthesis of pyrazolo[3,4‐d]pyrimidin‐3‐ones from 2,4‐dinitrophenylhydrazine and diethyl malonate under microwave irradiation in 1,3‐dibutylimidazolium bromide ionic liquid. The synthesized compounds were analyzed by elemental analysis and standard spectroscopic techniques. The compounds were screened for their antibacterial and antifungal activities. |
| doi_str_mv | 10.1002/jhet.3587 |
| format | Article |
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| language | eng |
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| source | Wiley Online Library Journals Frontfile Complete |
| subjects | Fungicides Heterocyclic compounds Ionic liquids Irradiation Pyrazolopyrimidines Synthesis |
| title | Synthesis of Some Substituted Pyrazolopyrimidine Derivatives: An Environmentally Benign Approach |
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