[kappa]-Opioid System Regulates the Long-Lasting Behavioral Adaptations Induced by Early-Life Exposure to Methylphenidate

Methylphenidate (MPH) is commonly prescribed in childhood and adolescence for the treatment of attention-deficit/hyperactivity disorders. In rodents, MPH exposure during preadolescence (postnatal days (PD) 20-35) causes decreased sensitivity to drug and natural rewards, while enhancing a negative em...

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Veröffentlicht in:	Neuropsychopharmacology (New York, N.Y.) N.Y.), 2009-04, Vol.34 (5), p.1339
Hauptverfasser:	Wiley, Matthew D, Poveromo, Laura B, Antapasis, John, Herrera, Carolina M, Bolaños Guzmán, Carlos A
Format:	Artikel
Sprache:	eng
Schlagworte:	Attention deficit hyperactivity disorder Cocaine Drug dosages Ligands Narcotics Neurosciences
Online-Zugang:	Volltext
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