Localized Palmar-Plantar Epidermal Hyperplasia Associated with Use of Sorafenib

A 45-year-old man receiving oral sorafenib 400 mg twice daily for metastatic renal cell carcinoma developed pain and rash on his hands and feet 3 weeks after commencement of treatment. Dermatological examination revealed hyperkeratotic plaques surrounded by erythema and with a callus-like brownish-y...

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Veröffentlicht in:	Clinical drug investigation 2008-01, Vol.28 (12), p.803-807
Hauptverfasser:	Cicek, Demet, Kandi, Basak, Dagli, Ferda A., Karaoglu, Aziz, Haligur, Beyzan D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - adverse effects Benzenesulfonates - adverse effects Carcinoma, Renal Cell - drug therapy Case Report Drug Eruptions - etiology Erythema - chemically induced Humans Internal Medicine Kidney Neoplasms - drug therapy Male Medicine Medicine & Public Health Middle Aged Niacinamide - analogs & derivatives Pharmacology/Toxicology Pharmacotherapy Phenylurea Compounds Pyridines - adverse effects
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