Central nervous system toxicity attributable to epidural ropivacaine hydrochloride
Ropivacaine, a new local anaesthetic agent, has been demonstrated to have less potential than bupivacaine for central nervous system toxicity on the basis of human and animal studies. We report a case of a convulsion secondary to presumed inadvertent intravascular injection of 20 mg of ropivacaine i...
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| Veröffentlicht in: | Anaesthesia and intensive care 1998-04, Vol.26 (2), p.204-206 |
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| container_title | Anaesthesia and intensive care |
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| creator | PLOWMAN, A. N BOLSIN, S MATHER, L. E |
| description | Ropivacaine, a new local anaesthetic agent, has been demonstrated to have less potential than bupivacaine for central nervous system toxicity on the basis of human and animal studies. We report a case of a convulsion secondary to presumed inadvertent intravascular injection of 20 mg of ropivacaine in a 44 kg patient during an epidural for chronic pain. There were minimal signs of cardiovascular toxicity. |
| doi_str_mv | 10.1177/0310057x9802600214 |
| format | Article |
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N</au><au>BOLSIN, S</au><au>MATHER, L. E</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Central nervous system toxicity attributable to epidural ropivacaine hydrochloride</atitle><jtitle>Anaesthesia and intensive care</jtitle><addtitle>Anaesth Intensive Care</addtitle><date>1998-04-01</date><risdate>1998</risdate><volume>26</volume><issue>2</issue><spage>204</spage><epage>206</epage><pages>204-206</pages><issn>0310-057X</issn><eissn>1448-0271</eissn><coden>AINCBS</coden><abstract>Ropivacaine, a new local anaesthetic agent, has been demonstrated to have less potential than bupivacaine for central nervous system toxicity on the basis of human and animal studies. We report a case of a convulsion secondary to presumed inadvertent intravascular injection of 20 mg of ropivacaine in a 44 kg patient during an epidural for chronic pain. 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| identifier | ISSN: 0310-057X |
| ispartof | Anaesthesia and intensive care, 1998-04, Vol.26 (2), p.204-206 |
| issn | 0310-057X 1448-0271 |
| language | eng |
| recordid | cdi_proquest_journals_224849753 |
| source | MEDLINE; Alma/SFX Local Collection |
| subjects | Adolescent Amides - administration & dosage Amides - adverse effects Anesthetics, Local - administration & dosage Anesthetics, Local - adverse effects Biological and medical sciences Drug toxicity and drugs side effects treatment Humans Injections, Epidural Male Medical sciences Pain, Intractable - drug therapy Pharmacology. Drug treatments Ropivacaine Seizures - chemically induced Toxicity: nervous system and muscle |
| title | Central nervous system toxicity attributable to epidural ropivacaine hydrochloride |
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