Acute lithium intoxication
We present a case of acute lithium intoxication in a 51-year-old woman on chronic lithium therapy. Her serum lithium level was 10.6 mmol/l 13 hours after ingestion and 5.8 mmol/l at 24 hours. Dialysis therapy was not employed and she recovered well after fluid resuscitation. Serum lithium levels in...
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| Veröffentlicht in: | Anaesthesia and intensive care 2002-02, Vol.30 (1), p.90-92 |
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| creator | NAGAPPAN, R PARKIN, W. G HOLDSWORTH, S. R |
| description | We present a case of acute lithium intoxication in a 51-year-old woman on chronic lithium therapy. Her serum lithium level was 10.6 mmol/l 13 hours after ingestion and 5.8 mmol/l at 24 hours. Dialysis therapy was not employed and she recovered well after fluid resuscitation. Serum lithium levels in chronic intoxication are more indicative of intracellular lithium concentration and therefore of clinical toxicity, as opposed to serum lithium levels in acute intoxication. Clinical features of toxicity are more important than a spot lithium level. A combination of clinical toxicity, the duration of exposure and a serial profile of serum lithium levels should guide dialytic therapy for removal of lithium. |
| doi_str_mv | 10.1177/0310057X0203000118 |
| format | Article |
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A combination of clinical toxicity, the duration of exposure and a serial profile of serum lithium levels should guide dialytic therapy for removal of lithium.</description><identifier>ISSN: 0310-057X</identifier><identifier>EISSN: 1448-0271</identifier><identifier>DOI: 10.1177/0310057X0203000118</identifier><identifier>PMID: 11939450</identifier><identifier>CODEN: AINCBS</identifier><language>eng</language><publisher>Edgecliff: Anaesthesia and Intensive Care</publisher><subject>Biological and medical sciences ; Drug intoxications. Doping ; Female ; Fluid Therapy ; Humans ; Lithium - blood ; Lithium - poisoning ; Medical sciences ; Middle Aged ; Pharmacology. 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A combination of clinical toxicity, the duration of exposure and a serial profile of serum lithium levels should guide dialytic therapy for removal of lithium.</description><subject>Biological and medical sciences</subject><subject>Drug intoxications. Doping</subject><subject>Female</subject><subject>Fluid Therapy</subject><subject>Humans</subject><subject>Lithium - blood</subject><subject>Lithium - poisoning</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Pharmacology. 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| subjects | Biological and medical sciences Drug intoxications. Doping Female Fluid Therapy Humans Lithium - blood Lithium - poisoning Medical sciences Middle Aged Pharmacology. Drug treatments Suicide, Attempted Treatment Outcome |
| title | Acute lithium intoxication |
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