1756-P: β-Cell Glucose Sensitivity and Intrapancreatic Adipose Tissue as Predictors of Diabetes Onset

Several evidences suggest that the functional β cell defects anticipate the onset of hyperglycemia and the reduction of mass. To assess whether the β-cell deterioration corresponds to a loss of β-cell mass, we performed glucose oral tolerance test (OGTT) and hyperglycemic clamp (HC) followed by argi...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2019-06, Vol.68
Hauptverfasser:	Cinti, Francesca, Mezza, Teresa, Cefalo, Chiara Maria Assunta, Sorice, Gian Pio, Moffa, Simona, Severi, Ilenia, Cinti, Saverio, Giaccari, Andrea
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipose tissue Arginine Beta cells Diabetes Diabetes mellitus Glucose Glucose tolerance Hyperglycemia Insulin Insulin secretion Pancreas Preservation Secretion Surgery
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