Aniline-induced methaemoglobinaemia in a glucose-6-phosphate dehydrogenase enzyme deficient patient

A case of methaemoglobinaemia following ingestion of an aniline-containing material is described. The detrimental effect of methylene blue, the classical antidote of methaemoglobinaemia, in a patient with glucose-6-phosphate dehydrogenase deficiency is highlighted.

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Bibliographische Detailangaben
Veröffentlicht in:	Anaesthesia and intensive care 2007-04, Vol.35 (2), p.286-288
Hauptverfasser:	MULLICK, P, KUMAR, A, DAYAL, M, BABBAR, S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anesthesia Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Aniline Aniline Compounds - adverse effects Biological and medical sciences Blood Gas Analysis - methods Blood Transfusion - methods Case studies Chemical properties Development and progression Diagnosis Dosage and administration Drug therapy Enzyme Inhibitors - administration & dosage Female Gastric Lavage - methods Glucose-6-phosphate dehydrogenase deficiency Glucosephosphate Dehydrogenase Deficiency - complications Health aspects Hemolysis Humans Intermittent Positive-Pressure Ventilation - methods Intubation, Intratracheal - methods Medical sciences Methemoglobinemia Methemoglobinemia - chemically induced Methemoglobinemia - complications Methemoglobinemia - therapy Methylene blue Methylene Blue - administration & dosage Oximetry - methods Oxygen - administration & dosage Oxygen - blood Patient outcomes
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Beschreibung
Zusammenfassung:	A case of methaemoglobinaemia following ingestion of an aniline-containing material is described. The detrimental effect of methylene blue, the classical antidote of methaemoglobinaemia, in a patient with glucose-6-phosphate dehydrogenase deficiency is highlighted.
ISSN:	0310-057X 1448-0271
DOI:	10.1177/0310057x0703500222