Effect of oleuropein on morphine-induced hippocampus neurotoxicity and memory impairments in rats

Oleuropein, as an olive leaf extract antioxidant polyphenol, has been reported to be a free radical scavenger. This study was done to investigate the effects of oleuropein, against morphine-induced hippocampus neurotoxicity and memory impairment in rats. The Morris water maze (MWM) test was used to...

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Veröffentlicht in:	Naunyn-Schmiedeberg's archives of pharmacology 2019-11, Vol.392 (11), p.1383-1391
Hauptverfasser:	Shibani, Farhad, Sahamsizadeh, Ali, Fatemi, Iman, Allahtavakoli, Mohammad, Hasanshahi, Jalal, Rahmani, Mohammadreza, Azin, Mahdieh, Hassanipour, Mahsa, Mozafari, Nazanin, Kaeidi, Ayat
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants Apoptosis BAX protein Biochemical markers Biomedical and Life Sciences Biomedicine Caspase Caspase-3 Glutathione peroxidase Hippocampus Malondialdehyde Memory Molecular modelling Morphine Neurosciences Neurotoxicity Oleuropein Original Article Oxidative stress Pharmacology/Toxicology Plant extracts Rodents Spatial discrimination learning Spatial memory Sulfates Superoxide dismutase
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