Development of a biomaterial made by hydroxyapatite and chlorhexidine for application to the oral cavity
Hydroxyapatite (HAp) is present in the human body in bone and dental tissues, which of the total mass of each tissue 30 to 70% correspond to HAp, and can be applied as coatings of prostheses or replacement of small bone parts. Thus, the objective was to synthesize HAp by precipitation, to incorporat...
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| Veröffentlicht in: | Cerâmica (São Paulo) 2019-01, Vol.65 (373), p.130 |
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| creator | dos Santos, M V B Feitosa, G T Osajima, J A Santos, R L P Filho, E C da Silva |
| description | Hydroxyapatite (HAp) is present in the human body in bone and dental tissues, which of the total mass of each tissue 30 to 70% correspond to HAp, and can be applied as coatings of prostheses or replacement of small bone parts. Thus, the objective was to synthesize HAp by precipitation, to incorporate chlorhexidine (CHX) and to evaluate the microbial properties. The characterization was performed by XRD, FTIR, TG/DTG, TEM and SEM. CHX was incorporated into the HAp by adsorption, varying the amount incorporated. The XRD pattern showed peaks at 25.9º, 31.5º, 32.2ºand 32.7º (2θ) for planes (002), (211), (112) and (300) of HAp. The FTIR spectrum showed band at 1050 cm-1 corresponding to the deformation of the phosphate groups and deformations of CH2 groups at 1485 and 1445 cm-1 of chlorhexidine, which presented porous and cylindrical morphology. The biomaterial showed excellent antimicrobial properties against Streptococcus mutans, Staphylococcus aureus and Escherichia coli. |
| doi_str_mv | 10.1590/0366-69132019653732441 |
| format | Magazinearticle |
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Thus, the objective was to synthesize HAp by precipitation, to incorporate chlorhexidine (CHX) and to evaluate the microbial properties. The characterization was performed by XRD, FTIR, TG/DTG, TEM and SEM. CHX was incorporated into the HAp by adsorption, varying the amount incorporated. The XRD pattern showed peaks at 25.9º, 31.5º, 32.2ºand 32.7º (2θ) for planes (002), (211), (112) and (300) of HAp. The FTIR spectrum showed band at 1050 cm-1 corresponding to the deformation of the phosphate groups and deformations of CH2 groups at 1485 and 1445 cm-1 of chlorhexidine, which presented porous and cylindrical morphology. 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| source | DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Bacteria Biomedical materials Chlorhexidine Deformation E coli Hydroxyapatite Microorganisms Morphology Prostheses Surgical implants |
| title | Development of a biomaterial made by hydroxyapatite and chlorhexidine for application to the oral cavity |
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