Brief report. Adenosine deaminase in childhood pulmonary tuberculosis: diagnostic value in serum

Brief report. Adenosine deaminase in childhood pulmonary tuberculosis: diagnostic value in serum

The diagnostic value of serum adenosine deaminase (ADA) activity was evaluated in childhood pulmonary tuberculosis. Serum ADA levels were measured in 20 children diagnosed with pulmonary tuberculosis (group 1) and 150 children (group 2) including 128 with tuberculosis infection (Mantoux test positiv...

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Veröffentlicht in:Journal of tropical pediatrics (1980) 1999-08, Vol.45 (4), p.245-247
Hauptverfasser: Kuyucu, N, Karakurt, C, Bilaloglu, E, Karacan, C, Teziç, T
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container_issue 4
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container_title Journal of tropical pediatrics (1980)
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creator Kuyucu, N
Karakurt, C
Bilaloglu, E
Karacan, C
Teziç, T
description The diagnostic value of serum adenosine deaminase (ADA) activity was evaluated in childhood pulmonary tuberculosis. Serum ADA levels were measured in 20 children diagnosed with pulmonary tuberculosis (group 1) and 150 children (group 2) including 128 with tuberculosis infection (Mantoux test positive) and 22 healthy children. In group 1, the mean serum ADA activity was 74.06 ± 18.5 U/l, which was significantly (p
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Adenosine deaminase in childhood pulmonary tuberculosis: diagnostic value in serum</title><source>Oxford University Press Journals All Titles (1996-Current)</source><creator>Kuyucu, N ; Karakurt, C ; Bilaloglu, E ; Karacan, C ; Teziç, T</creator><creatorcontrib>Kuyucu, N ; Karakurt, C ; Bilaloglu, E ; Karacan, C ; Teziç, T</creatorcontrib><description>The diagnostic value of serum adenosine deaminase (ADA) activity was evaluated in childhood pulmonary tuberculosis. Serum ADA levels were measured in 20 children diagnosed with pulmonary tuberculosis (group 1) and 150 children (group 2) including 128 with tuberculosis infection (Mantoux test positive) and 22 healthy children. In group 1, the mean serum ADA activity was 74.06 ± 18.5 U/l, which was significantly (p&lt;0.001) higher than that of group 2 (40.36 ± 12.0 U/l). Serum ADA level of ⩾53.76 U/l had a sensitivity of 100 per cent, specificity of 90.7 per cent, positive predictive value of 58.8 per cent, and a negative predictive value of 100 per cent in children with tuberculosis disease. 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title Brief report. Adenosine deaminase in childhood pulmonary tuberculosis: diagnostic value in serum
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