High susceptibility of chromosome 16 to radiation-induced chromosome rearrangements in human lymphocytes under in vivo and in vitro exposure

The aim of the present study was to investigate whether chromosome 16p presents breakpoint regions susceptible to radiation-induced rearrangements. The frequencies of translocations were determined by fluorescence in situ hybridization (FISH) using cosmid probes C40 and C55 mapping on chromosome 16p...

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Veröffentlicht in:	Cytogenetic and genome research 2005-01, Vol.108 (4), p.287-292
Hauptverfasser:	Camparoto, M.L., Takahashi-Hyodo, S.A., Dauwerse, J.G., Natarajan, A.T., Sakamoto-Hojo, E.T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Brazil - epidemiology Cells, Cultured Cesium Radioisotopes - adverse effects Chromosome Painting - methods Chromosomes, Human, Pair 16 - genetics Chromosomes, Human, Pair 16 - radiation effects Female Gene Rearrangement - genetics Gene Rearrangement - radiation effects Humans In Situ Hybridization, Fluorescence - methods Lymphocytes - chemistry Lymphocytes - cytology Lymphocytes - metabolism Lymphocytes - radiation effects Male Middle Aged Original Article Radiation Dosage Radioactive Hazard Release Time Translocation, Genetic - radiation effects
Online-Zugang:	Volltext
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