Eukaryotic translation initiation factor 3 subunit G (EI F3G) resensitized HC T116/5-Fu to 5-fluorouracil (5-Fu) via inhibition of MRP and MDR1

Purpose: Colorectal cancer (CRC) has become a predominant cancer and accounts for approximately 10% of cancer-related mortality. Drug resistance still remains a priority mortality factor for patients due to no available therapeutic alternatives. The purpose of the present study was to investigate th...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	OncoTargets and therapy 2018-08, Vol.11, p.5315-5324
Hauptverfasser:	Yang, Chenggang, Liu, Xin, Li, Chaobin, Li, Shuangjing, Du, Wenfeng, Yang, Daogui
Format:	Artikel
Sprache:	eng
Schlagworte:	5-Fluorouracil Apoptosis Breast cancer Cell growth Colorectal cancer Drug resistance Glycoproteins Initiation factor eIF-3 Laboratories Membranes Polymerase chain reaction Proteins Xenografts
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!