Inverted duplication pattern in anaphase bridges confirms the breakage-fusion-bridge (BFB) cycle model for 11q13 amplification

The homogeneously staining region (hsr) involving chromosome band 11q13 includes amplified genes from this chromosome segment and carries a relatively poor prognosis in oral squamous cell carcinomas (OSCC), with shorter time to recurrence and reduced overall survival. We previously identified an inv...

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Veröffentlicht in:	Cytogenetic and genome research 2007-01, Vol.116 (1-2), p.46-52
Hauptverfasser:	Reshmi, S.C., Roychoudhury, S., Yu, Z., Feingold, E., Potter, D., Saunders, W.S., Gollin, S.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaphase Biomarkers - chemistry Carcinoma, Squamous Cell - genetics Cell Line Cell Line, Tumor Chromosomes, Human, Pair 11 DNA Damage Exons Gene Duplication Gene Library Humans In Situ Hybridization, Fluorescence Models, Genetic Mouth Neoplasms - genetics Oligonucleotide Probes Original Article
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