Efficient Synthesis of ( R )-Phenylephrine Using a Polymer-supported Corey–Bakshi–Shibata Catalyst

An efficient and mild synthetic route to (R)-phenylephrine hydrochloride using Corey–Bakshi–Shibata (CBS) catalyst was reported. In order to avoid a lengthy recovery process of the catalyst from homogeneous reaction, a polymer-supported CBS catalyst was prepared, and a preliminary attempt was made t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Chemistry letters 2017, Vol.46 (5), p.740-743
Hauptverfasser:	Dai, Shuangxiong, Li, Guohua, Zhang, Wenbo, Zhang, Cuiyan, Song, Xiaoling, Huang, Di
Format:	Artikel
Sprache:	eng
Schlagworte:	Catalysis Catalysts Chemical synthesis Polymers
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

container_end_page	743
container_issue	5
container_start_page	740
container_title	Chemistry letters
container_volume	46
creator	Dai, Shuangxiong Li, Guohua Zhang, Wenbo Zhang, Cuiyan Song, Xiaoling Huang, Di
description	An efficient and mild synthetic route to (R)-phenylephrine hydrochloride using Corey–Bakshi–Shibata (CBS) catalyst was reported. In order to avoid a lengthy recovery process of the catalyst from homogeneous reaction, a polymer-supported CBS catalyst was prepared, and a preliminary attempt was made to achieve a continuous reduction on a laboratory scale, which contributes to synthesis of (R)-phenylephrine in a cost-effective way.
doi_str_mv	10.1246/cl.170028
format	Article
fullrecord	<record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2241366013</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2241366013</sourcerecordid><originalsourceid>FETCH-LOGICAL-c457t-3b728c8471256a743ab454b940d25c2efa6acc2ab41f6db20b5a81364b93087e3</originalsourceid><addsrcrecordid>eNotkMtOwzAQRS0EEqWw4A8ssaELF79iu0uIykOqREXp2nJcm7ikSbDTRXb9B_6QLyGobOaOro5mpAPANcFTQrm4s9WUSIypOgEjwrhCWJLsFIwwEwJJTOk5uEhpizFWM0ZHwM-9Dza4uoOrvu5Kl0KCjYe38A1O0LJ0dV-5toyhdnCdQv0BDVw2Vb9zEaV92zaxcxuYN9H1P4fvB_OZyjAsqzIUpjMwH0bVp-4SnHlTJXf1n2Owfpy_589o8fr0kt8vkOWZ7BArJFVWcUloJozkzBQ848WM4w3NLHXeCGMtHVrixaaguMiMIkwMCMNKOjYGN8e7bWy-9i51etvsYz281JTygRSYsIGaHCkbm5Si87qNYWdirwnWfxq1rfRRI_sFrlpmaA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2241366013</pqid></control><display><type>article</type><title>Efficient Synthesis of ( R )-Phenylephrine Using a Polymer-supported Corey–Bakshi–Shibata Catalyst</title><source>Oxford University Press Journals All Titles (1996-Current)</source><creator>Dai, Shuangxiong ; Li, Guohua ; Zhang, Wenbo ; Zhang, Cuiyan ; Song, Xiaoling ; Huang, Di</creator><creatorcontrib>Dai, Shuangxiong ; Li, Guohua ; Zhang, Wenbo ; Zhang, Cuiyan ; Song, Xiaoling ; Huang, Di</creatorcontrib><description>An efficient and mild synthetic route to (R)-phenylephrine hydrochloride using Corey–Bakshi–Shibata (CBS) catalyst was reported. In order to avoid a lengthy recovery process of the catalyst from homogeneous reaction, a polymer-supported CBS catalyst was prepared, and a preliminary attempt was made to achieve a continuous reduction on a laboratory scale, which contributes to synthesis of (R)-phenylephrine in a cost-effective way.</description><identifier>ISSN: 0366-7022</identifier><identifier>EISSN: 1348-0715</identifier><identifier>DOI: 10.1246/cl.170028</identifier><language>eng</language><publisher>Tokyo: Chemical Society of Japan</publisher><subject>Catalysis ; Catalysts ; Chemical synthesis ; Polymers</subject><ispartof>Chemistry letters, 2017, Vol.46 (5), p.740-743</ispartof><rights>Copyright Chemical Society of Japan 2017</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c457t-3b728c8471256a743ab454b940d25c2efa6acc2ab41f6db20b5a81364b93087e3</citedby><cites>FETCH-LOGICAL-c457t-3b728c8471256a743ab454b940d25c2efa6acc2ab41f6db20b5a81364b93087e3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,4010,27900,27901,27902</link.rule.ids></links><search><creatorcontrib>Dai, Shuangxiong</creatorcontrib><creatorcontrib>Li, Guohua</creatorcontrib><creatorcontrib>Zhang, Wenbo</creatorcontrib><creatorcontrib>Zhang, Cuiyan</creatorcontrib><creatorcontrib>Song, Xiaoling</creatorcontrib><creatorcontrib>Huang, Di</creatorcontrib><title>Efficient Synthesis of ( R )-Phenylephrine Using a Polymer-supported Corey–Bakshi–Shibata Catalyst</title><title>Chemistry letters</title><description>An efficient and mild synthetic route to (R)-phenylephrine hydrochloride using Corey–Bakshi–Shibata (CBS) catalyst was reported. In order to avoid a lengthy recovery process of the catalyst from homogeneous reaction, a polymer-supported CBS catalyst was prepared, and a preliminary attempt was made to achieve a continuous reduction on a laboratory scale, which contributes to synthesis of (R)-phenylephrine in a cost-effective way.</description><subject>Catalysis</subject><subject>Catalysts</subject><subject>Chemical synthesis</subject><subject>Polymers</subject><issn>0366-7022</issn><issn>1348-0715</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><recordid>eNotkMtOwzAQRS0EEqWw4A8ssaELF79iu0uIykOqREXp2nJcm7ikSbDTRXb9B_6QLyGobOaOro5mpAPANcFTQrm4s9WUSIypOgEjwrhCWJLsFIwwEwJJTOk5uEhpizFWM0ZHwM-9Dza4uoOrvu5Kl0KCjYe38A1O0LJ0dV-5toyhdnCdQv0BDVw2Vb9zEaV92zaxcxuYN9H1P4fvB_OZyjAsqzIUpjMwH0bVp-4SnHlTJXf1n2Owfpy_589o8fr0kt8vkOWZ7BArJFVWcUloJozkzBQ848WM4w3NLHXeCGMtHVrixaaguMiMIkwMCMNKOjYGN8e7bWy-9i51etvsYz281JTygRSYsIGaHCkbm5Si87qNYWdirwnWfxq1rfRRI_sFrlpmaA</recordid><startdate>2017</startdate><enddate>2017</enddate><creator>Dai, Shuangxiong</creator><creator>Li, Guohua</creator><creator>Zhang, Wenbo</creator><creator>Zhang, Cuiyan</creator><creator>Song, Xiaoling</creator><creator>Huang, Di</creator><general>Chemical Society of Japan</general><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>8BQ</scope><scope>8FD</scope><scope>JG9</scope></search><sort><creationdate>2017</creationdate><title>Efficient Synthesis of ( R )-Phenylephrine Using a Polymer-supported Corey–Bakshi–Shibata Catalyst</title><author>Dai, Shuangxiong ; Li, Guohua ; Zhang, Wenbo ; Zhang, Cuiyan ; Song, Xiaoling ; Huang, Di</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c457t-3b728c8471256a743ab454b940d25c2efa6acc2ab41f6db20b5a81364b93087e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Catalysis</topic><topic>Catalysts</topic><topic>Chemical synthesis</topic><topic>Polymers</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Dai, Shuangxiong</creatorcontrib><creatorcontrib>Li, Guohua</creatorcontrib><creatorcontrib>Zhang, Wenbo</creatorcontrib><creatorcontrib>Zhang, Cuiyan</creatorcontrib><creatorcontrib>Song, Xiaoling</creatorcontrib><creatorcontrib>Huang, Di</creatorcontrib><collection>CrossRef</collection><collection>Engineered Materials Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>Materials Research Database</collection><jtitle>Chemistry letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Dai, Shuangxiong</au><au>Li, Guohua</au><au>Zhang, Wenbo</au><au>Zhang, Cuiyan</au><au>Song, Xiaoling</au><au>Huang, Di</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Efficient Synthesis of ( R )-Phenylephrine Using a Polymer-supported Corey–Bakshi–Shibata Catalyst</atitle><jtitle>Chemistry letters</jtitle><date>2017</date><risdate>2017</risdate><volume>46</volume><issue>5</issue><spage>740</spage><epage>743</epage><pages>740-743</pages><issn>0366-7022</issn><eissn>1348-0715</eissn><abstract>An efficient and mild synthetic route to (R)-phenylephrine hydrochloride using Corey–Bakshi–Shibata (CBS) catalyst was reported. In order to avoid a lengthy recovery process of the catalyst from homogeneous reaction, a polymer-supported CBS catalyst was prepared, and a preliminary attempt was made to achieve a continuous reduction on a laboratory scale, which contributes to synthesis of (R)-phenylephrine in a cost-effective way.</abstract><cop>Tokyo</cop><pub>Chemical Society of Japan</pub><doi>10.1246/cl.170028</doi><tpages>4</tpages><oa>free_for_read</oa></addata></record>
fulltext	fulltext
identifier	ISSN: 0366-7022
ispartof	Chemistry letters, 2017, Vol.46 (5), p.740-743
issn	0366-7022 1348-0715
language	eng
recordid	cdi_proquest_journals_2241366013
source	Oxford University Press Journals All Titles (1996-Current)
subjects	Catalysis Catalysts Chemical synthesis Polymers
title	Efficient Synthesis of ( R )-Phenylephrine Using a Polymer-supported Corey–Bakshi–Shibata Catalyst
url	https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-16T08%3A40%3A41IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Efficient%20Synthesis%20of%20(%20R%20)-Phenylephrine%20Using%20a%20Polymer-supported%20Corey%E2%80%93Bakshi%E2%80%93Shibata%20Catalyst&rft.jtitle=Chemistry%20letters&rft.au=Dai,%20Shuangxiong&rft.date=2017&rft.volume=46&rft.issue=5&rft.spage=740&rft.epage=743&rft.pages=740-743&rft.issn=0366-7022&rft.eissn=1348-0715&rft_id=info:doi/10.1246/cl.170028&rft_dat=%3Cproquest_cross%3E2241366013%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2241366013&rft_id=info:pmid/&rfr_iscdi=true