Endogenous Hormones and the Risk of Hip and Vertebral Fractures among Older Women
In postmenopausal women, vertebral fractures are often attributed to low estrogen production, and hip fractures to secondary hyperparathyroidism due to age-related declines in calcium intake and in calcium absorption mediated by 1,25-dihydroxyvitamin D (1,25(OH) 2 vitamin D). 1 , 2 The results of re...
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Veröffentlicht in: | The New England journal of medicine 1998-09, Vol.339 (11), p.733-738 |
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container_title | The New England journal of medicine |
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creator | Cummings, Steven R Browner, Warren S Bauer, Douglas Stone, Katie Ensrud, Kristine Jamal, Sophie Ettinger, Bruce |
description | In postmenopausal women, vertebral fractures are often attributed to low estrogen production, and hip fractures to secondary hyperparathyroidism due to age-related declines in calcium intake and in calcium absorption mediated by 1,25-dihydroxyvitamin D (1,25(OH)
2
vitamin D).
1
,
2
The results of retrospective case–control studies of the association between these hormones and the incidence of hip or vertebral fracture are conflicting, because of the alterations in serum hormone or vitamin D concentrations that result from fracture, the selection of nonrepresentative case and control subjects, and the use of insensitive assays for serum estradiol.
3
–
11
To determine the effects of endogenous hormones . . . |
doi_str_mv | 10.1056/NEJM199809103391104 |
format | Article |
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2
vitamin D).
1
,
2
The results of retrospective case–control studies of the association between these hormones and the incidence of hip or vertebral fracture are conflicting, because of the alterations in serum hormone or vitamin D concentrations that result from fracture, the selection of nonrepresentative case and control subjects, and the use of insensitive assays for serum estradiol.
3
–
11
To determine the effects of endogenous hormones . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199809103391104</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Biological and medical sciences ; Bone density ; Fractures ; Hormones. Endocrine system ; Medical sciences ; Older people ; Pharmacology. Drug treatments ; Vitamin D ; Women</subject><ispartof>The New England journal of medicine, 1998-09, Vol.339 (11), p.733-738</ispartof><rights>Copyright © 1998 Massachusetts Medical Society. All rights reserved.</rights><rights>1998 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c523t-efd43d4e8514d2e38a1a63ec9d666f24cfe5140dbde052be00eea4f407422e393</citedby><cites>FETCH-LOGICAL-c523t-efd43d4e8514d2e38a1a63ec9d666f24cfe5140dbde052be00eea4f407422e393</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199809103391104$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199809103391104$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2373593$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Cummings, Steven R</creatorcontrib><creatorcontrib>Browner, Warren S</creatorcontrib><creatorcontrib>Bauer, Douglas</creatorcontrib><creatorcontrib>Stone, Katie</creatorcontrib><creatorcontrib>Ensrud, Kristine</creatorcontrib><creatorcontrib>Jamal, Sophie</creatorcontrib><creatorcontrib>Ettinger, Bruce</creatorcontrib><title>Endogenous Hormones and the Risk of Hip and Vertebral Fractures among Older Women</title><title>The New England journal of medicine</title><description>In postmenopausal women, vertebral fractures are often attributed to low estrogen production, and hip fractures to secondary hyperparathyroidism due to age-related declines in calcium intake and in calcium absorption mediated by 1,25-dihydroxyvitamin D (1,25(OH)
2
vitamin D).
1
,
2
The results of retrospective case–control studies of the association between these hormones and the incidence of hip or vertebral fracture are conflicting, because of the alterations in serum hormone or vitamin D concentrations that result from fracture, the selection of nonrepresentative case and control subjects, and the use of insensitive assays for serum estradiol.
3
–
11
To determine the effects of endogenous hormones . . .</description><subject>Biological and medical sciences</subject><subject>Bone density</subject><subject>Fractures</subject><subject>Hormones. Endocrine system</subject><subject>Medical sciences</subject><subject>Older people</subject><subject>Pharmacology. Drug treatments</subject><subject>Vitamin D</subject><subject>Women</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1998</creationdate><recordtype>article</recordtype><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kEtLAzEUhYMoWKu_wE0QdzKa1zyylNJapVoUH8shndzUqTNJTWYW_ntTW1yJd3Ph3u-cAwehU0ouKUmzq4fx3T2VsiCSEs4lpUTsoQFNOU-EINk-GhDCikTkkh-ioxBWJA4VcoAex1a7JVjXBzx1vnUWAlZW4-4d8FMdPrAzeFqvf26v4DtYeNXgiVdV1_sNGyVLPG80ePzmWrDH6MCoJsDJbg_Ry2T8PJoms_nN7eh6llQp410CRguuBRQpFZoBLxRVGYdK6izLDBOVgfgheqGBpGwBhAAoYQTJBYu45EN0tvVde_fZQ-jKleu9jZElY1zmTBZ5hPgWqrwLwYMp175ulf8qKSk31ZV_VBdV5ztrFSrVGK9sVYdfKeM5TyWP2MUWa9tQWli1_5p-A-sxeX4</recordid><startdate>19980910</startdate><enddate>19980910</enddate><creator>Cummings, Steven R</creator><creator>Browner, Warren S</creator><creator>Bauer, Douglas</creator><creator>Stone, Katie</creator><creator>Ensrud, Kristine</creator><creator>Jamal, Sophie</creator><creator>Ettinger, Bruce</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>19980910</creationdate><title>Endogenous Hormones and the Risk of Hip and Vertebral Fractures among Older Women</title><author>Cummings, Steven R ; Browner, Warren S ; Bauer, Douglas ; Stone, Katie ; Ensrud, Kristine ; Jamal, Sophie ; Ettinger, Bruce</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c523t-efd43d4e8514d2e38a1a63ec9d666f24cfe5140dbde052be00eea4f407422e393</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1998</creationdate><topic>Biological and medical sciences</topic><topic>Bone density</topic><topic>Fractures</topic><topic>Hormones. Endocrine system</topic><topic>Medical sciences</topic><topic>Older people</topic><topic>Pharmacology. Drug treatments</topic><topic>Vitamin D</topic><topic>Women</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Cummings, Steven R</creatorcontrib><creatorcontrib>Browner, Warren S</creatorcontrib><creatorcontrib>Bauer, Douglas</creatorcontrib><creatorcontrib>Stone, Katie</creatorcontrib><creatorcontrib>Ensrud, Kristine</creatorcontrib><creatorcontrib>Jamal, Sophie</creatorcontrib><creatorcontrib>Ettinger, Bruce</creatorcontrib><collection>Pascal-Francis</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Cummings, Steven R</au><au>Browner, Warren S</au><au>Bauer, Douglas</au><au>Stone, Katie</au><au>Ensrud, Kristine</au><au>Jamal, Sophie</au><au>Ettinger, Bruce</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Endogenous Hormones and the Risk of Hip and Vertebral Fractures among Older Women</atitle><jtitle>The New England journal of medicine</jtitle><date>1998-09-10</date><risdate>1998</risdate><volume>339</volume><issue>11</issue><spage>733</spage><epage>738</epage><pages>733-738</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>In postmenopausal women, vertebral fractures are often attributed to low estrogen production, and hip fractures to secondary hyperparathyroidism due to age-related declines in calcium intake and in calcium absorption mediated by 1,25-dihydroxyvitamin D (1,25(OH)
2
vitamin D).
1
,
2
The results of retrospective case–control studies of the association between these hormones and the incidence of hip or vertebral fracture are conflicting, because of the alterations in serum hormone or vitamin D concentrations that result from fracture, the selection of nonrepresentative case and control subjects, and the use of insensitive assays for serum estradiol.
3
–
11
To determine the effects of endogenous hormones . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJM199809103391104</doi><tpages>6</tpages><oa>free_for_read</oa></addata></record> |
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source | EZB-FREE-00999 freely available EZB journals; New England Journal of Medicine Current |
subjects | Biological and medical sciences Bone density Fractures Hormones. Endocrine system Medical sciences Older people Pharmacology. Drug treatments Vitamin D Women |
title | Endogenous Hormones and the Risk of Hip and Vertebral Fractures among Older Women |
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