Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia
Unsustained ventricular tachycardia in patients who have had a previous myocardial infarction and have left ventricular dysfunction has been associated with a two-year mortality rate in the range of 30 percent. 1 – 3 Antiarrhythmic therapy has been widely used for unsustained ventricular tachycardia...
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| Veröffentlicht in: | The New England journal of medicine 1996-12, Vol.335 (26), p.1933-1940 |
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| container_end_page | 1940 |
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| container_issue | 26 |
| container_start_page | 1933 |
| container_title | The New England journal of medicine |
| container_volume | 335 |
| creator | Moss, Arthur J Hall, W. Jackson Cannom, David S Daubert, James P Higgins, Steven L Klein, Helmut Levine, Joseph H Saksena, Sanjeev Waldo, Albert L Wilber, David Brown, Mary W Heo, Moonseong |
| description | Unsustained ventricular tachycardia in patients who have had a previous myocardial infarction and have left ventricular dysfunction has been associated with a two-year mortality rate in the range of 30 percent.
1
–
3
Antiarrhythmic therapy has been widely used for unsustained ventricular tachycardia, but there has been no evidence of improved survival with this treatment.
4
–
6
In December 1990, we initiated a prophylactic trial in which high-risk patients with coronary heart disease and asymptomatic unsustained ventricular tachycardia were randomly assigned to receive an implantable cardioverter–defibrillator or conventional medical therapy. To ensure a population at high risk for malignant ventricular arrhythmias,
7
, . . . |
| doi_str_mv | 10.1056/NEJM199612263352601 |
| format | Article |
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1
–
3
Antiarrhythmic therapy has been widely used for unsustained ventricular tachycardia, but there has been no evidence of improved survival with this treatment.
4
–
6
In December 1990, we initiated a prophylactic trial in which high-risk patients with coronary heart disease and asymptomatic unsustained ventricular tachycardia were randomly assigned to receive an implantable cardioverter–defibrillator or conventional medical therapy. To ensure a population at high risk for malignant ventricular arrhythmias,
7
, . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199612263352601</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Biological and medical sciences ; Cardiac arrhythmia ; Cardiovascular disease ; Diseases of the cardiovascular system ; Heart attacks ; Medical sciences ; Mortality ; Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)</subject><ispartof>The New England journal of medicine, 1996-12, Vol.335 (26), p.1933-1940</ispartof><rights>Copyright © 1996 Massachusetts Medical Society. All rights reserved.</rights><rights>1997 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c475t-6042f163191358c41faba9e92dabd3a5bd094c299e37402ad97b5f124c60fd103</citedby><cites>FETCH-LOGICAL-c475t-6042f163191358c41faba9e92dabd3a5bd094c299e37402ad97b5f124c60fd103</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199612263352601$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM199612263352601$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26080,27901,27902,52357,54039</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=2520645$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Moss, Arthur J</creatorcontrib><creatorcontrib>Hall, W. Jackson</creatorcontrib><creatorcontrib>Cannom, David S</creatorcontrib><creatorcontrib>Daubert, James P</creatorcontrib><creatorcontrib>Higgins, Steven L</creatorcontrib><creatorcontrib>Klein, Helmut</creatorcontrib><creatorcontrib>Levine, Joseph H</creatorcontrib><creatorcontrib>Saksena, Sanjeev</creatorcontrib><creatorcontrib>Waldo, Albert L</creatorcontrib><creatorcontrib>Wilber, David</creatorcontrib><creatorcontrib>Brown, Mary W</creatorcontrib><creatorcontrib>Heo, Moonseong</creatorcontrib><title>Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia</title><title>The New England journal of medicine</title><description>Unsustained ventricular tachycardia in patients who have had a previous myocardial infarction and have left ventricular dysfunction has been associated with a two-year mortality rate in the range of 30 percent.
1
–
3
Antiarrhythmic therapy has been widely used for unsustained ventricular tachycardia, but there has been no evidence of improved survival with this treatment.
4
–
6
In December 1990, we initiated a prophylactic trial in which high-risk patients with coronary heart disease and asymptomatic unsustained ventricular tachycardia were randomly assigned to receive an implantable cardioverter–defibrillator or conventional medical therapy. To ensure a population at high risk for malignant ventricular arrhythmias,
7
, . . .</description><subject>Biological and medical sciences</subject><subject>Cardiac arrhythmia</subject><subject>Cardiovascular disease</subject><subject>Diseases of the cardiovascular system</subject><subject>Heart attacks</subject><subject>Medical sciences</subject><subject>Mortality</subject><subject>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. 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Jackson ; Cannom, David S ; Daubert, James P ; Higgins, Steven L ; Klein, Helmut ; Levine, Joseph H ; Saksena, Sanjeev ; Waldo, Albert L ; Wilber, David ; Brown, Mary W ; Heo, Moonseong</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c475t-6042f163191358c41faba9e92dabd3a5bd094c299e37402ad97b5f124c60fd103</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1996</creationdate><topic>Biological and medical sciences</topic><topic>Cardiac arrhythmia</topic><topic>Cardiovascular disease</topic><topic>Diseases of the cardiovascular system</topic><topic>Heart attacks</topic><topic>Medical sciences</topic><topic>Mortality</topic><topic>Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. 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Jackson</au><au>Cannom, David S</au><au>Daubert, James P</au><au>Higgins, Steven L</au><au>Klein, Helmut</au><au>Levine, Joseph H</au><au>Saksena, Sanjeev</au><au>Waldo, Albert L</au><au>Wilber, David</au><au>Brown, Mary W</au><au>Heo, Moonseong</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia</atitle><jtitle>The New England journal of medicine</jtitle><date>1996-12-26</date><risdate>1996</risdate><volume>335</volume><issue>26</issue><spage>1933</spage><epage>1940</epage><pages>1933-1940</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>Unsustained ventricular tachycardia in patients who have had a previous myocardial infarction and have left ventricular dysfunction has been associated with a two-year mortality rate in the range of 30 percent.
1
–
3
Antiarrhythmic therapy has been widely used for unsustained ventricular tachycardia, but there has been no evidence of improved survival with this treatment.
4
–
6
In December 1990, we initiated a prophylactic trial in which high-risk patients with coronary heart disease and asymptomatic unsustained ventricular tachycardia were randomly assigned to receive an implantable cardioverter–defibrillator or conventional medical therapy. To ensure a population at high risk for malignant ventricular arrhythmias,
7
, . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><doi>10.1056/NEJM199612263352601</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 1996-12, Vol.335 (26), p.1933-1940 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_journals_223971937 |
| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; New England Journal of Medicine |
| subjects | Biological and medical sciences Cardiac arrhythmia Cardiovascular disease Diseases of the cardiovascular system Heart attacks Medical sciences Mortality Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects) |
| title | Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia |
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