A Double-Blind Trial of a 16-Hour Transdermal Nicotine Patch in Smoking Cessation
TO date, the use of nicotine chewing gum combined with psychological support during the initial months of quitting smoking is the only treatment that has been shown to increase long-term rates of quitting, as compared with placebo. 1 , 2 Of six trials that have assessed the efficacy of a 24-hour tra...
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| Veröffentlicht in: | The New England journal of medicine 1991-08, Vol.325 (5), p.311-315 |
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| container_end_page | 315 |
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| container_issue | 5 |
| container_start_page | 311 |
| container_title | The New England journal of medicine |
| container_volume | 325 |
| creator | Tonnesen, Philip Norregaard, Jesper Simonsen, Kåre Säwe, Urbain |
| description | TO date, the use of nicotine chewing gum combined with psychological support during the initial months of quitting smoking is the only treatment that has been shown to increase long-term rates of quitting, as compared with placebo.
1
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Of six trials that have assessed the efficacy of a 24-hour transdermal nicotine patch, a significant increase in short-term cessation was found in five.
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There are a number of important differences between nicotine chewing gum and the nicotine patch. The gum is often used as the smoker wishes, and chewing may itself be of therapeutic value, even if it is associated with some . . . |
| doi_str_mv | 10.1056/NEJM199108013250503 |
| format | Article |
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1
,
2
Of six trials that have assessed the efficacy of a 24-hour transdermal nicotine patch, a significant increase in short-term cessation was found in five.
3
4
5
6
7
8
There are a number of important differences between nicotine chewing gum and the nicotine patch. The gum is often used as the smoker wishes, and chewing may itself be of therapeutic value, even if it is associated with some . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM199108013250503</identifier><identifier>PMID: 2057036</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Administration, Cutaneous ; Adult ; Aged ; Alcohol ; Behavior ; Behavior Therapy ; Biological and medical sciences ; Body Weight ; Carbon monoxide ; Chewing Gum ; Double-Blind Method ; Double-blind studies ; Drug abuse ; Drug addiction ; Drug dosages ; Female ; Humans ; Male ; Medical research ; Medical sciences ; Middle Aged ; Nicotine ; Nicotine - administration & dosage ; Nicotine - adverse effects ; Patient Compliance ; Skin ; Smoking ; Smoking cessation ; Smoking Prevention ; Substance abuse treatment ; Substance Withdrawal Syndrome ; Tobacco, tobacco smoking ; Toxicology ; Transdermal medication</subject><ispartof>The New England journal of medicine, 1991-08, Vol.325 (5), p.311-315</ispartof><rights>1992 INIST-CNRS</rights><rights>Copyright Massachusetts Medical Society Aug 1, 1991</rights><rights>Copyright Massachusetts Medical Society, Publishing Division Aug 1, 1991</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c568t-2331b2b193564ad763bb5c4c0cca91693b9910b08b6e0df62e48a14eec2763c83</citedby><cites>FETCH-LOGICAL-c568t-2331b2b193564ad763bb5c4c0cca91693b9910b08b6e0df62e48a14eec2763c83</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM199108013250503$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/223953038?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,776,780,2745,2746,26082,27903,27904,52361,54043,64362,64366,72216</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=4969839$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/2057036$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tonnesen, Philip</creatorcontrib><creatorcontrib>Norregaard, Jesper</creatorcontrib><creatorcontrib>Simonsen, Kåre</creatorcontrib><creatorcontrib>Säwe, Urbain</creatorcontrib><title>A Double-Blind Trial of a 16-Hour Transdermal Nicotine Patch in Smoking Cessation</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>TO date, the use of nicotine chewing gum combined with psychological support during the initial months of quitting smoking is the only treatment that has been shown to increase long-term rates of quitting, as compared with placebo.
1
,
2
Of six trials that have assessed the efficacy of a 24-hour transdermal nicotine patch, a significant increase in short-term cessation was found in five.
3
4
5
6
7
8
There are a number of important differences between nicotine chewing gum and the nicotine patch. The gum is often used as the smoker wishes, and chewing may itself be of therapeutic value, even if it is associated with some . . .</description><subject>Administration, Cutaneous</subject><subject>Adult</subject><subject>Aged</subject><subject>Alcohol</subject><subject>Behavior</subject><subject>Behavior Therapy</subject><subject>Biological and medical sciences</subject><subject>Body Weight</subject><subject>Carbon monoxide</subject><subject>Chewing Gum</subject><subject>Double-Blind Method</subject><subject>Double-blind studies</subject><subject>Drug abuse</subject><subject>Drug addiction</subject><subject>Drug dosages</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Medical research</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nicotine</subject><subject>Nicotine - administration & dosage</subject><subject>Nicotine - adverse effects</subject><subject>Patient Compliance</subject><subject>Skin</subject><subject>Smoking</subject><subject>Smoking cessation</subject><subject>Smoking Prevention</subject><subject>Substance abuse treatment</subject><subject>Substance Withdrawal Syndrome</subject><subject>Tobacco, tobacco smoking</subject><subject>Toxicology</subject><subject>Transdermal medication</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kE1PGzEQhq2qKA20vwBVsig3tHTssZ31MQ3hS2naqnBe2V4vOOxHWG8O_Ps6SsQJOpeR5n3m6yXkmME5A6m-L-e3P5nWDHJgyCVIwA9kzCRiJgSoj2QMwPNMTDR-IocxriAFE3pERhzkBFCNyZ8pveg2tvbZjzq0Jb3rg6lpV1FDmcquu02fSqaNpe-bJCyD64bQevrbDO6Rhpb-bbqn0D7QmY_RDKFrP5ODytTRf9nnI3J_Ob-bXWeLX1c3s-kic1LlQ8YRmeWWaZRKmHKi0FrphAPnjGZKo91-ZiG3ykNZKe5Fbpjw3vHEuhyPyMlu7rrvnjc-DsUqXdumlQXnqCUCbqFv70FM5yhwohRLFO4o13cx9r4q1n1oTP9SMCi2VhdvWJ26vu5nb2zjy9eevbdJP93rJjpTV8lGF-IrJrRKF-iEne2wpolF61fNf5f-A_PSjmE</recordid><startdate>19910801</startdate><enddate>19910801</enddate><creator>Tonnesen, Philip</creator><creator>Norregaard, Jesper</creator><creator>Simonsen, Kåre</creator><creator>Säwe, Urbain</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>19910801</creationdate><title>A Double-Blind Trial of a 16-Hour Transdermal Nicotine Patch in Smoking Cessation</title><author>Tonnesen, Philip ; Norregaard, Jesper ; Simonsen, Kåre ; Säwe, Urbain</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c568t-2331b2b193564ad763bb5c4c0cca91693b9910b08b6e0df62e48a14eec2763c83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Administration, Cutaneous</topic><topic>Adult</topic><topic>Aged</topic><topic>Alcohol</topic><topic>Behavior</topic><topic>Behavior Therapy</topic><topic>Biological and medical sciences</topic><topic>Body Weight</topic><topic>Carbon monoxide</topic><topic>Chewing Gum</topic><topic>Double-Blind Method</topic><topic>Double-blind studies</topic><topic>Drug abuse</topic><topic>Drug addiction</topic><topic>Drug dosages</topic><topic>Female</topic><topic>Humans</topic><topic>Male</topic><topic>Medical research</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nicotine</topic><topic>Nicotine - administration & dosage</topic><topic>Nicotine - adverse effects</topic><topic>Patient Compliance</topic><topic>Skin</topic><topic>Smoking</topic><topic>Smoking cessation</topic><topic>Smoking Prevention</topic><topic>Substance abuse treatment</topic><topic>Substance Withdrawal Syndrome</topic><topic>Tobacco, tobacco smoking</topic><topic>Toxicology</topic><topic>Transdermal medication</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tonnesen, Philip</creatorcontrib><creatorcontrib>Norregaard, Jesper</creatorcontrib><creatorcontrib>Simonsen, Kåre</creatorcontrib><creatorcontrib>Säwe, Urbain</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>ProQuest Psychology</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tonnesen, Philip</au><au>Norregaard, Jesper</au><au>Simonsen, Kåre</au><au>Säwe, Urbain</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Double-Blind Trial of a 16-Hour Transdermal Nicotine Patch in Smoking Cessation</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>1991-08-01</date><risdate>1991</risdate><volume>325</volume><issue>5</issue><spage>311</spage><epage>315</epage><pages>311-315</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>TO date, the use of nicotine chewing gum combined with psychological support during the initial months of quitting smoking is the only treatment that has been shown to increase long-term rates of quitting, as compared with placebo.
1
,
2
Of six trials that have assessed the efficacy of a 24-hour transdermal nicotine patch, a significant increase in short-term cessation was found in five.
3
4
5
6
7
8
There are a number of important differences between nicotine chewing gum and the nicotine patch. The gum is often used as the smoker wishes, and chewing may itself be of therapeutic value, even if it is associated with some . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>2057036</pmid><doi>10.1056/NEJM199108013250503</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 1991-08, Vol.325 (5), p.311-315 |
| issn | 0028-4793 1533-4406 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; ProQuest Central UK/Ireland; New England Journal of Medicine |
| subjects | Administration, Cutaneous Adult Aged Alcohol Behavior Behavior Therapy Biological and medical sciences Body Weight Carbon monoxide Chewing Gum Double-Blind Method Double-blind studies Drug abuse Drug addiction Drug dosages Female Humans Male Medical research Medical sciences Middle Aged Nicotine Nicotine - administration & dosage Nicotine - adverse effects Patient Compliance Skin Smoking Smoking cessation Smoking Prevention Substance abuse treatment Substance Withdrawal Syndrome Tobacco, tobacco smoking Toxicology Transdermal medication |
| title | A Double-Blind Trial of a 16-Hour Transdermal Nicotine Patch in Smoking Cessation |
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