Improvement by Acetylcysteine of Hemodynamics and Oxygen Transport in Fulminant Hepatic Failure

IN normal subjects tissue oxygen consumption is maintained at around 110 ml per minute per square meter of body-surface area, and changes in oxygen delivery are counterbalanced by reciprocal changes in the proportion of oxygen extracted. In critically ill patients tissue oxygen consumption becomes d...

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Veröffentlicht in:	The New England journal of medicine 1991-06, Vol.324 (26), p.1852-1857
Hauptverfasser:	Harrison, Phillip M, Wendon, Julia A, Gimson, Alexander E.S, Alexander, Graeme J.M, Williams, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetaminophen Acetaminophen - poisoning Acetylcysteine Acetylcysteine - administration & dosage Acetylcysteine - pharmacology Acetylcysteine - therapeutic use Adolescent Adult Analgesics Biological and medical sciences Biological Transport - drug effects Blood pressure Body weight Chemical and Drug Induced Liver Injury - etiology Circulatory system Dextrose Digestive system Drug Overdose Endothelium Female Glutathione Heart diseases Hemodynamics Hemodynamics - drug effects Hepatic Encephalopathy - drug therapy Hepatic Encephalopathy - physiopathology Hepatitis Hepatitis C - complications Hepatitis, Alcoholic - complications Humans Hypotheses Hypoxia Intravenous administration Laboratories Liver Liver failure Male Medical prognosis Medical sciences Metabolism Middle Aged Neutrophils Overdose Oxygen Oxygen - metabolism Oxygen consumption Oxygen Consumption - drug effects Pathogenesis Pharmacology. Drug treatments Pulmonary arteries Survival Veins & arteries Ventilators
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