Temporal Aspects of Heparin-Induced Thrombocytopenia

Heparin-induced thrombocytopenia is a syndrome of antibody-mediated thrombocytopenia that paradoxically is often associated with thrombosis. 1 – 5 Most patients with this disorder produce IgG antibodies 6 , 7 against complexes of platelet factor 4 and heparin. 8 – 11 Platelet factor 4, a small pepti...

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