Inhaled Iloprost for Severe Pulmonary Hypertension

The number of effective, long-term treatments for pulmonary hypertension is limited. In this double-blind, randomized trial, an aerosolized form of iloprost, a stable analogue of the pulmonary vasodilator prostacyclin, was assessed over a 12-week period. Iloprost had a beneficial effect on the combi...

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Veröffentlicht in:	The New England journal of medicine 2002-08, Vol.347 (5), p.322-329
Hauptverfasser:	Olschewski, Horst, Simonneau, Gerald, Galiè, Nazzareno, Higenbottam, Timothy, Naeije, Robert, Rubin, Lewis J, Nikkho, Sylvia, Speich, Rudolf, Hoeper, Marius M, Behr, Jürgen, Winkler, Jörg, Sitbon, Olivier, Popov, Wladimir, Ghofrani, H. Ardeschir, Manes, Alessandra, Kiely, David G, Ewert, Ralph, Meyer, Andreas, Corris, Paul A, Delcroix, Marion, Gomez-Sanchez, Miguel, Siedentop, Harald, Seeger, Werner
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Inhalation Biological and medical sciences Drug therapy Dyspnea - drug therapy Dyspnea - etiology Exercise Tolerance - drug effects Female Hemodynamics - drug effects Hemophilia Humans Hypertension Hypertension, Pulmonary - classification Hypertension, Pulmonary - drug therapy Hypertension, Pulmonary - physiopathology Iloprost - administration & dosage Iloprost - adverse effects Male Medical sciences Middle Aged Mortality Nitric oxide Pharmacology. Drug treatments Pulmonary arteries Respiratory system Vasodilator Agents - administration & dosage Vasodilator Agents - adverse effects Walking
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