A Comparison of Nefazodone, the Cognitive Behavioral-Analysis System of Psychotherapy, and Their Combination for the Treatment of Chronic Depression

Traditionally thought of as an episodic, remitting illness, major depressive disorder often has a chronic course, with protracted episodes or incomplete remission between episodes. 1 – 3 At any given time, at least 3 percent of the U.S. population suffers from chronic depression. 4 , 5 Chronic forms...

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Veröffentlicht in:The New England journal of medicine 2000-05, Vol.342 (20), p.1462-1470
Hauptverfasser: Keller, Martin B, McCullough, James P, Klein, Daniel N, Arnow, Bruce, Dunner, David L, Gelenberg, Alan J, Markowitz, John C, Nemeroff, Charles B, Russell, James M, Thase, Michael E, Trivedi, Madhukar H, Blalock, Janice A, Borian, Frances E, Jody, Darlene N, DeBattista, Charles, Koran, Lorrin M, Schatzberg, Alan F, Fawcett, Jan, Hirschfeld, Robert M.A, Keitner, Gabor, Miller, Ivan, Kocsis, James H, Kornstein, Susan G, Manber, Rachel, Ninan, Philip T, Rothbaum, Barbara, Rush, A. John, Vivian, Dina, Zajecka, John
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container_issue 20
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container_title The New England journal of medicine
container_volume 342
creator Keller, Martin B
McCullough, James P
Klein, Daniel N
Arnow, Bruce
Dunner, David L
Gelenberg, Alan J
Markowitz, John C
Nemeroff, Charles B
Russell, James M
Thase, Michael E
Trivedi, Madhukar H
Blalock, Janice A
Borian, Frances E
Jody, Darlene N
DeBattista, Charles
Koran, Lorrin M
Schatzberg, Alan F
Fawcett, Jan
Hirschfeld, Robert M.A
Keitner, Gabor
Miller, Ivan
Kocsis, James H
Kornstein, Susan G
Manber, Rachel
Ninan, Philip T
Rothbaum, Barbara
Rush, A. John
Vivian, Dina
Zajecka, John
description Traditionally thought of as an episodic, remitting illness, major depressive disorder often has a chronic course, with protracted episodes or incomplete remission between episodes. 1 – 3 At any given time, at least 3 percent of the U.S. population suffers from chronic depression. 4 , 5 Chronic forms of major depression are associated with more marked impairments in psychosocial function and work performance, 6 – 8 increased health care utilization, 5 , 9 and more frequent suicide attempts and hospitalization 10 than acute depression. Because they frequently begin early in life 11 and are often lifelong, chronic forms of major depression account for an inordinate proportion of the enormous burden . . .
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subjects Adult
Antidepressive Agents, Second-Generation - adverse effects
Antidepressive Agents, Second-Generation - therapeutic use
Behavior modification
Behavior Therapy
Chronic Disease
Cognitive Therapy - methods
Combined Modality Therapy
Depressive Disorder - drug therapy
Depressive Disorder - therapy
Drug therapy
Female
Humans
Male
Mental depression
Psychology
Treatment Outcome
Triazoles - adverse effects
Triazoles - therapeutic use
title A Comparison of Nefazodone, the Cognitive Behavioral-Analysis System of Psychotherapy, and Their Combination for the Treatment of Chronic Depression
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