A Comparison of Nefazodone, the Cognitive Behavioral-Analysis System of Psychotherapy, and Their Combination for the Treatment of Chronic Depression
Traditionally thought of as an episodic, remitting illness, major depressive disorder often has a chronic course, with protracted episodes or incomplete remission between episodes. 1 – 3 At any given time, at least 3 percent of the U.S. population suffers from chronic depression. 4 , 5 Chronic forms...
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creator | Keller, Martin B McCullough, James P Klein, Daniel N Arnow, Bruce Dunner, David L Gelenberg, Alan J Markowitz, John C Nemeroff, Charles B Russell, James M Thase, Michael E Trivedi, Madhukar H Blalock, Janice A Borian, Frances E Jody, Darlene N DeBattista, Charles Koran, Lorrin M Schatzberg, Alan F Fawcett, Jan Hirschfeld, Robert M.A Keitner, Gabor Miller, Ivan Kocsis, James H Kornstein, Susan G Manber, Rachel Ninan, Philip T Rothbaum, Barbara Rush, A. John Vivian, Dina Zajecka, John |
description | Traditionally thought of as an episodic, remitting illness, major depressive disorder often has a chronic course, with protracted episodes or incomplete remission between episodes.
1
–
3
At any given time, at least 3 percent of the U.S. population suffers from chronic depression.
4
,
5
Chronic forms of major depression are associated with more marked impairments in psychosocial function and work performance,
6
–
8
increased health care utilization,
5
,
9
and more frequent suicide attempts and hospitalization
10
than acute depression. Because they frequently begin early in life
11
and are often lifelong, chronic forms of major depression account for an inordinate proportion of the enormous burden . . . |
doi_str_mv | 10.1056/NEJM200005183422001 |
format | Article |
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1
–
3
At any given time, at least 3 percent of the U.S. population suffers from chronic depression.
4
,
5
Chronic forms of major depression are associated with more marked impairments in psychosocial function and work performance,
6
–
8
increased health care utilization,
5
,
9
and more frequent suicide attempts and hospitalization
10
than acute depression. Because they frequently begin early in life
11
and are often lifelong, chronic forms of major depression account for an inordinate proportion of the enormous burden . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJM200005183422001</identifier><identifier>PMID: 10816183</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Adult ; Antidepressive Agents, Second-Generation - adverse effects ; Antidepressive Agents, Second-Generation - therapeutic use ; Behavior modification ; Behavior Therapy ; Chronic Disease ; Cognitive Therapy - methods ; Combined Modality Therapy ; Depressive Disorder - drug therapy ; Depressive Disorder - therapy ; Drug therapy ; Female ; Humans ; Male ; Mental depression ; Psychology ; Treatment Outcome ; Triazoles - adverse effects ; Triazoles - therapeutic use</subject><ispartof>The New England journal of medicine, 2000-05, Vol.342 (20), p.1462-1470</ispartof><rights>Copyright © 2000 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c500t-78ead662afd3b7475935126b0bda88c34c162caf5a752a4976805861ed5412403</citedby><cites>FETCH-LOGICAL-c500t-78ead662afd3b7475935126b0bda88c34c162caf5a752a4976805861ed5412403</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJM200005183422001$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.nejm.org/doi/full/10.1056/NEJM200005183422001$$EHTML$$P50$$Gmms$$H</linktohtml><link.rule.ids>314,776,780,2746,2747,26082,27903,27904,52360,54042</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10816183$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Keller, Martin B</creatorcontrib><creatorcontrib>McCullough, James P</creatorcontrib><creatorcontrib>Klein, Daniel N</creatorcontrib><creatorcontrib>Arnow, Bruce</creatorcontrib><creatorcontrib>Dunner, David L</creatorcontrib><creatorcontrib>Gelenberg, Alan J</creatorcontrib><creatorcontrib>Markowitz, John C</creatorcontrib><creatorcontrib>Nemeroff, Charles B</creatorcontrib><creatorcontrib>Russell, James M</creatorcontrib><creatorcontrib>Thase, Michael E</creatorcontrib><creatorcontrib>Trivedi, Madhukar H</creatorcontrib><creatorcontrib>Blalock, Janice A</creatorcontrib><creatorcontrib>Borian, Frances E</creatorcontrib><creatorcontrib>Jody, Darlene N</creatorcontrib><creatorcontrib>DeBattista, Charles</creatorcontrib><creatorcontrib>Koran, Lorrin M</creatorcontrib><creatorcontrib>Schatzberg, Alan F</creatorcontrib><creatorcontrib>Fawcett, Jan</creatorcontrib><creatorcontrib>Hirschfeld, Robert M.A</creatorcontrib><creatorcontrib>Keitner, Gabor</creatorcontrib><creatorcontrib>Miller, Ivan</creatorcontrib><creatorcontrib>Kocsis, James H</creatorcontrib><creatorcontrib>Kornstein, Susan G</creatorcontrib><creatorcontrib>Manber, Rachel</creatorcontrib><creatorcontrib>Ninan, Philip T</creatorcontrib><creatorcontrib>Rothbaum, Barbara</creatorcontrib><creatorcontrib>Rush, A. John</creatorcontrib><creatorcontrib>Vivian, Dina</creatorcontrib><creatorcontrib>Zajecka, John</creatorcontrib><title>A Comparison of Nefazodone, the Cognitive Behavioral-Analysis System of Psychotherapy, and Their Combination for the Treatment of Chronic Depression</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>Traditionally thought of as an episodic, remitting illness, major depressive disorder often has a chronic course, with protracted episodes or incomplete remission between episodes.
1
–
3
At any given time, at least 3 percent of the U.S. population suffers from chronic depression.
4
,
5
Chronic forms of major depression are associated with more marked impairments in psychosocial function and work performance,
6
–
8
increased health care utilization,
5
,
9
and more frequent suicide attempts and hospitalization
10
than acute depression. Because they frequently begin early in life
11
and are often lifelong, chronic forms of major depression account for an inordinate proportion of the enormous burden . . .</description><subject>Adult</subject><subject>Antidepressive Agents, Second-Generation - adverse effects</subject><subject>Antidepressive Agents, Second-Generation - therapeutic use</subject><subject>Behavior modification</subject><subject>Behavior Therapy</subject><subject>Chronic Disease</subject><subject>Cognitive Therapy - methods</subject><subject>Combined Modality Therapy</subject><subject>Depressive Disorder - drug therapy</subject><subject>Depressive Disorder - therapy</subject><subject>Drug therapy</subject><subject>Female</subject><subject>Humans</subject><subject>Male</subject><subject>Mental depression</subject><subject>Psychology</subject><subject>Treatment Outcome</subject><subject>Triazoles - adverse effects</subject><subject>Triazoles - therapeutic use</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp9kctu1DAUQC0EokPhC5CQxbYN-J1kOUxLAZWCxLCObpIb4tHEDnamUviOfnAdpgsWqN7Yks85kn0Jec3ZO860eX9z-eWrYGlpXkgl0pE_ISuupcyUYuYpWTEmikzlpTwhL2LcLSxX5XNywlnBTbJW5G5NN34YIdjoHfUdvcEO_vjWOzynU4_p9pezk71F-gF7uLU-wD5bO9jP0Ub6Y44TDov3Pc5N75MRYJzPKbiWbnu0YcnX1sFkU7_z4W90GxCmAd20mJs-eGcbeoFjwBgT95I862Af8dXDfkp-frzcbj5l19-uPm_W11mjGZuyvEBojRHQtbLOVa5LqbkwNatbKIpGqoYb0UCnIdcCVJmbgunCcGy14kIxeUreHrtj8L8PGKdq5w8hvS1WQshSilLoBMkj1AQfY8CuGoMdIMwVZ9UyiOo_g0jWm4f0oR6w_cc5_nwCzo7AMMTK4W54NHcPeSiQFg</recordid><startdate>20000518</startdate><enddate>20000518</enddate><creator>Keller, Martin B</creator><creator>McCullough, James P</creator><creator>Klein, Daniel N</creator><creator>Arnow, Bruce</creator><creator>Dunner, David L</creator><creator>Gelenberg, Alan J</creator><creator>Markowitz, John C</creator><creator>Nemeroff, Charles B</creator><creator>Russell, James M</creator><creator>Thase, Michael E</creator><creator>Trivedi, Madhukar H</creator><creator>Blalock, Janice A</creator><creator>Borian, Frances E</creator><creator>Jody, Darlene N</creator><creator>DeBattista, Charles</creator><creator>Koran, Lorrin M</creator><creator>Schatzberg, Alan F</creator><creator>Fawcett, Jan</creator><creator>Hirschfeld, Robert M.A</creator><creator>Keitner, Gabor</creator><creator>Miller, Ivan</creator><creator>Kocsis, James H</creator><creator>Kornstein, Susan G</creator><creator>Manber, Rachel</creator><creator>Ninan, Philip T</creator><creator>Rothbaum, Barbara</creator><creator>Rush, A. 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John</au><au>Vivian, Dina</au><au>Zajecka, John</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A Comparison of Nefazodone, the Cognitive Behavioral-Analysis System of Psychotherapy, and Their Combination for the Treatment of Chronic Depression</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2000-05-18</date><risdate>2000</risdate><volume>342</volume><issue>20</issue><spage>1462</spage><epage>1470</epage><pages>1462-1470</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>Traditionally thought of as an episodic, remitting illness, major depressive disorder often has a chronic course, with protracted episodes or incomplete remission between episodes.
1
–
3
At any given time, at least 3 percent of the U.S. population suffers from chronic depression.
4
,
5
Chronic forms of major depression are associated with more marked impairments in psychosocial function and work performance,
6
–
8
increased health care utilization,
5
,
9
and more frequent suicide attempts and hospitalization
10
than acute depression. Because they frequently begin early in life
11
and are often lifelong, chronic forms of major depression account for an inordinate proportion of the enormous burden . . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>10816183</pmid><doi>10.1056/NEJM200005183422001</doi><tpages>9</tpages><oa>free_for_read</oa></addata></record> |
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subjects | Adult Antidepressive Agents, Second-Generation - adverse effects Antidepressive Agents, Second-Generation - therapeutic use Behavior modification Behavior Therapy Chronic Disease Cognitive Therapy - methods Combined Modality Therapy Depressive Disorder - drug therapy Depressive Disorder - therapy Drug therapy Female Humans Male Mental depression Psychology Treatment Outcome Triazoles - adverse effects Triazoles - therapeutic use |
title | A Comparison of Nefazodone, the Cognitive Behavioral-Analysis System of Psychotherapy, and Their Combination for the Treatment of Chronic Depression |
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