A Multicenter, Randomized, Controlled Trial of Dexamethasone for Bronchiolitis

Infants with a first episode of wheezing diagnosed as bronchiolitis are often treated with oral dexamethasone. In this trial, children with bronchiolitis and no history of asthma received oral dexamethasone or placebo. There were no clinically significant differences in outcomes between the two grou...

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Veröffentlicht in:	The New England journal of medicine 2007-07, Vol.357 (4), p.331-339
Hauptverfasser:	Corneli, Howard M, Zorc, Joseph J, Mahajan, Prashant, Shaw, Kathy N, Holubkov, Richard, Reeves, Scott D, Ruddy, Richard M, Malik, Baqir, Nelson, Kyle A, Bregstein, Joan S, Brown, Kathleen M, Denenberg, Matthew N, Lillis, Kathleen A, Cimpello, Lynn Babcock, Tsung, James W, Borgialli, Dominic A, Baskin, Marc N, Teshome, Getachew, Goldstein, Mitchell A, Monroe, David, Dean, J. Michael, Kuppermann, Nathan
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Babies Biological and medical sciences Bronchiolitis - drug therapy Bronchiolitis - physiopathology Chronic obstructive pulmonary disease, asthma Clinical outcomes Clinical trials Dexamethasone - administration & dosage Dexamethasone - adverse effects Dexamethasone - therapeutic use Double-Blind Method Drug therapy Emergency Service, Hospital Female General aspects Glucocorticoids - administration & dosage Glucocorticoids - adverse effects Glucocorticoids - therapeutic use Hospitalization Hospitalization - statistics & numerical data Humans Infant Male Medical sciences Pneumology Prescription drugs Respiration Respiratory diseases Respiratory Sounds - drug effects Treatment Failure
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