Azithromycin for the Secondary Prevention of Coronary Events

Since Chlamydia pneumoniae is believed to be involved in the pathogenesis of coronary artery disease, this study investigated whether antibiotic therapy with azithromycin to eliminate C. pneumoniae would reduce the risk of coronary events. There was no beneficial effect associated with azithromycin....

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Veröffentlicht in:	The New England journal of medicine 2005-04, Vol.352 (16), p.1637-1645
Hauptverfasser:	Grayston, J. Thomas, Kronmal, Richard A, Jackson, Lisa A, Parisi, Alfred F, Muhlestein, Joseph B, Cohen, Jerome D, Rogers, William J, Crouse, John R, Borrowdale, Sandra L, Schron, Eleanor, Knirsch, Charles
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anti-Bacterial Agents - adverse effects Anti-Bacterial Agents - therapeutic use Antibiotics Azithromycin - adverse effects Azithromycin - therapeutic use Cardiovascular disease Chlamydophila Infections - drug therapy Chlamydophila pneumoniae Clinical trials Coronary Disease - drug therapy Coronary Disease - mortality Coronary Disease - prevention & control Coronary vessels Double-Blind Method Drug therapy Female Hearing Loss - chemically induced Humans Male Middle Aged Myocardial Infarction - prevention & control Myocardial Revascularization Prospective Studies
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