Antibodies Neutralizing Peginterferon Alfa during Retreatment of Hepatitis C

To the Editor: Peginterferons are widely used to treat chronic hepatitis C virus (HCV) infection, an important cause of liver cirrhosis and hepatocellular carcinoma. 1 – 4 We describe a patient who did not have a virologic response to peginterferon and had a virtual absence of circulating peginterfe...

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