A Trial of Combination Antimalarial Therapies in Children from Papua New Guinea

In this open-label study of four regimens (chloroquine–sulfadoxine–pyrimethamine, artesunate–sulfadoxine–pyrimethamine, dihydroartemisinin–piperaquine, and artemether–lumefantrine) to treat children with malaria in Papua New Guinea, artemether–lumefantrine was found to be the most efficacious for tr...

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Veröffentlicht in:	The New England journal of medicine 2008-12, Vol.359 (24), p.2545-2557
Hauptverfasser:	Karunajeewa, Harin A, Mueller, Ivo, Senn, Michele, Lin, Enmoore, Law, Irwin, Gomorrai, P. Servina, Oa, Olive, Griffin, Suzanne, Kotab, Kaye, Suano, Penias, Tarongka, Nandao, Ura, Alice, Lautu, Dulcie, Page-Sharp, Madhu, Wong, Rina, Salman, Sam, Siba, Peter, Ilett, Kenneth F, Davis, Timothy M.E
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibiotics. Antiinfectious agents. Antiparasitic agents Antimalarials - adverse effects Antimalarials - therapeutic use Antiparasitic agents Artemisinins - therapeutic use Biological and medical sciences Child, Preschool Chloroquine - therapeutic use Drug therapy Drug Therapy, Combination Ethanolamines - therapeutic use Female Fluorenes - therapeutic use General aspects Health facilities Humans Infant Kaplan-Meier Estimate Malaria Malaria, Falciparum - drug therapy Malaria, Vivax - drug therapy Male Medical sciences Pharmacology. Drug treatments Proportional Hazards Models Pyrimethamine - therapeutic use Quinolines - therapeutic use Recurrence Sulfadoxine - therapeutic use
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