Gastric Cancer in Japan
To the Editor: In their Perspective article (July 31 issue), 1 Forman and Pisani ask, “Why does gastric cancer occur so frequently in Japan?” One answer was proposed more than 30 years ago by Matsudo et al., 2 who detected talc in the normal gastric mucosa and in gastric cancers in Japanese patients...
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| Veröffentlicht in: | The New England journal of medicine 2008-11, Vol.359 (22), p.2393-2395 |
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| container_title | The New England journal of medicine |
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| creator | Horowitz, Richard E |
| description | To the Editor:
In their Perspective article (July 31 issue),
1
Forman and Pisani ask, “Why does gastric cancer occur so frequently in Japan?” One answer was proposed more than 30 years ago by Matsudo et al.,
2
who detected talc in the normal gastric mucosa and in gastric cancers in Japanese patients and suggested a causal relationship.
Talc is used in Japan to polish rice, and it is customary to wash off the talc before cooking the rice. However, if the washing is insufficient, talc is ingested. Talc is a hydrated magnesium silicate with the chemical formula H
2
Mg
3
. . . |
| doi_str_mv | 10.1056/NEJMc081797 |
| format | Article |
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In their Perspective article (July 31 issue),
1
Forman and Pisani ask, “Why does gastric cancer occur so frequently in Japan?” One answer was proposed more than 30 years ago by Matsudo et al.,
2
who detected talc in the normal gastric mucosa and in gastric cancers in Japanese patients and suggested a causal relationship.
Talc is used in Japan to polish rice, and it is customary to wash off the talc before cooking the rice. However, if the washing is insufficient, talc is ingested. Talc is a hydrated magnesium silicate with the chemical formula H
2
Mg
3
. . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMc081797</identifier><identifier>PMID: 19038888</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>United States: Massachusetts Medical Society</publisher><subject>Humans ; Japan - epidemiology ; Oryza ; Risk Factors ; Stomach Neoplasms - chemically induced ; Stomach Neoplasms - epidemiology ; Talc - adverse effects</subject><ispartof>The New England journal of medicine, 2008-11, Vol.359 (22), p.2393-2395</ispartof><rights>Copyright © 2008 Massachusetts Medical Society. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c381t-c29c2d51612f5c91040b22c9ab64aa3dc9398eedaf676f1c6d4c76b191c849f53</citedby><cites>FETCH-LOGICAL-c381t-c29c2d51612f5c91040b22c9ab64aa3dc9398eedaf676f1c6d4c76b191c849f53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMc081797$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/223920955?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,2759,2760,26103,27924,27925,52382,54064,64385,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19038888$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Horowitz, Richard E</creatorcontrib><title>Gastric Cancer in Japan</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>To the Editor:
In their Perspective article (July 31 issue),
1
Forman and Pisani ask, “Why does gastric cancer occur so frequently in Japan?” One answer was proposed more than 30 years ago by Matsudo et al.,
2
who detected talc in the normal gastric mucosa and in gastric cancers in Japanese patients and suggested a causal relationship.
Talc is used in Japan to polish rice, and it is customary to wash off the talc before cooking the rice. However, if the washing is insufficient, talc is ingested. Talc is a hydrated magnesium silicate with the chemical formula H
2
Mg
3
. . .</description><subject>Humans</subject><subject>Japan - epidemiology</subject><subject>Oryza</subject><subject>Risk Factors</subject><subject>Stomach Neoplasms - chemically induced</subject><subject>Stomach Neoplasms - epidemiology</subject><subject>Talc - adverse effects</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNptkDFPwzAQhS0EoqUwMbChCkYU8NmOkxurqBSqAgvMlnNxpEQkKXYz8O9JlUow8JZbPn1P9xi7BH4PPNYPr8v1C_EUEkyO2BRiKSOluD5mU85FGqkE5YSdhVDzIaDwlE0AuUyHTNnVyoadr2ie2Zacn1ftfG23tj1nJ6X9DO7icGfs43H5nj1Fm7fVc7bYRCRT2EUkkEQRgwZRxoTAFc-FILS5VtbKglBi6lxhS53oEkgXihKdAwKlCstYztjN6N367qt3YWfqrvftUGmEkCg4xnvoboTIdyF4V5qtrxrrvw1ws9_A_NlgoK8Pyj5vXPHLHp4egNsRaJpgWlc3_2p-AAY7XnM</recordid><startdate>20081127</startdate><enddate>20081127</enddate><creator>Horowitz, Richard E</creator><general>Massachusetts Medical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>20081127</creationdate><title>Gastric Cancer in Japan</title><author>Horowitz, Richard E</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c381t-c29c2d51612f5c91040b22c9ab64aa3dc9398eedaf676f1c6d4c76b191c849f53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Humans</topic><topic>Japan - 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In their Perspective article (July 31 issue),
1
Forman and Pisani ask, “Why does gastric cancer occur so frequently in Japan?” One answer was proposed more than 30 years ago by Matsudo et al.,
2
who detected talc in the normal gastric mucosa and in gastric cancers in Japanese patients and suggested a causal relationship.
Talc is used in Japan to polish rice, and it is customary to wash off the talc before cooking the rice. However, if the washing is insufficient, talc is ingested. Talc is a hydrated magnesium silicate with the chemical formula H
2
Mg
3
. . .</abstract><cop>United States</cop><pub>Massachusetts Medical Society</pub><pmid>19038888</pmid><doi>10.1056/NEJMc081797</doi><tpages>3</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0028-4793 |
| ispartof | The New England journal of medicine, 2008-11, Vol.359 (22), p.2393-2395 |
| issn | 0028-4793 1533-4406 |
| language | eng |
| recordid | cdi_proquest_journals_223920955 |
| source | MEDLINE; New England Journal of Medicine Current; EZB-FREE-00999 freely available EZB journals; ProQuest Central UK/Ireland |
| subjects | Humans Japan - epidemiology Oryza Risk Factors Stomach Neoplasms - chemically induced Stomach Neoplasms - epidemiology Talc - adverse effects |
| title | Gastric Cancer in Japan |
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