A multi-epitope synthetic peptic and recombinant protein for the detection of antibodies to Trypanosoma cruzi in radioimmunoprecipitation-confirmed and consenus-positive sera

Peptide epitopes of Trypanosoma cruzi have been identified through expression cloning. A tripeptide (2/D/E) containing three epitopes (TcD, TcE, PEP-2) was used in ELISA to detect antibodies to T. cruzi in 239 of 240 consensus-positive sera and 41 of 42 sera confirmed positive by radioimmunoprecipit...

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Veröffentlicht in:The Journal of infectious diseases 1999-05, Vol.179 (5), p.1226
Hauptverfasser: Houghton, Raymond L, Benson, Darin R, Reynolds, Lisa D, McNeill, Patricia D
Format: Artikel
Sprache:eng
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