rDEN4[Delta]30, a Live Attenuated Dengue Virus Type 4 Vaccine Candidate, Is Safe, Immunogenic, and Highly Infectious in Healthy Adult Volunteers

BACKGROUND: The live attenuated dengue virus type 4 (DEN-4) vaccine candidate virus rDEN4 Delta 30 was previously found to be safe and immunogenic at a dose of 10(5) plaque-forming units (pfu). METHODS: In a follow-up placebo-controlled phase 2 clinical trial, rDEN4 Delta 30 was administered as a si...

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Veröffentlicht in:The Journal of infectious diseases 2005-03, Vol.191 (5), p.710
Hauptverfasser: Durbin, Anna P, Whitehead, Stephen S, McArthur, Julie, Perreault, John R
Format: Artikel
Sprache:eng
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