S100P regulates the collective invasion of pancreatic cancer cells into the lymphatic endothelial monolayer

Lymph node metastasis is an independent prognostic factor in pancreatic cancer. However, the mechanisms of lymph node colonization are unknown. As a mechanism of lymphatic metastasis, it has been reported for other types of cancer that spheroids from tumor cells cause circular chemorepellent‑induced...

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Veröffentlicht in:	International journal of oncology 2019-07, Vol.55 (1), p.211-222
Hauptverfasser:	Nakayama, Hiromichi, Ohuchida, Kenoki, Yonenaga, Akiko, Sagara, Akiko, Ando, Yohei, Kibe, Shin, Takesue, Shin, Abe, Toshiya, Endo, Sho, Koikawa, Kazuhiro, Okumura, Takashi, Shido, Koji, Miyoshi, Kei, Nakata, Kohei, Moriyama, Taiki, Miyasaka, Yoshihiro, Inoue, Shigetaka, Ohtsuka, Takao, Mizumoto, Kazuhiro, Nakamura, Masafumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Animals Antigens, Nuclear - metabolism Autoantigens - metabolism Cancer cells Cancer metastasis Cancer research Cell adhesion & migration Cell Adhesion - physiology Cell Line, Tumor DNA microarrays Endothelial Cells - metabolism Endothelial Cells - pathology Endothelium Female Humans Immunohistochemistry Instrument industry (Equipment) Lymph Nodes - metabolism Lymph Nodes - pathology Lymphatic Metastasis Lymphatic system Male Metastasis Mice Middle Aged Neoplasm Invasiveness Pancreatic cancer Pancreatic Neoplasms - metabolism Pancreatic Neoplasms - pathology Patients Peptides Pharmaceutical industry Prognosis Protein binding Proteins Scientific equipment industry Spheroids Spheroids, Cellular Tumors
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